about
Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.Use of comprehensive screening methods to detect selective human CAR activators.Applicability of Generic Assays Based on Liquid Chromatography-Electrospray Mass Spectrometry to Study in vitro Metabolism of 55 Structurally Diverse Compounds.Comparison of triple quadrupole, hybrid linear ion trap triple quadrupole, time-of-flight and LTQ-Orbitrap mass spectrometers in drug discovery phase metabolite screening and identification in vitro--amitriptyline and verapamil as model compounds.Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis.Comparison of unit resolution SRM and TOF-MS at 12,000 mass resolution for quantitative bioanalysis of 11 steroids from human plasma.Effects of cell differentiation and assay conditions on the UDP-glucuronosyltransferase activity in Caco-2 cellsCharacterization of cyanide-trapped methylated metabonates formed during reactive drug metabolite screening in vitro
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Q33410164-C88B92AE-64CB-4B84-9822-EBA8A8FF7133Q34021094-0E990A06-DCCF-4029-8863-538B9DD76378Q42733644-764A85BF-B1F6-4E3C-A27B-5E2D5847E5C6Q43139798-54A99B70-71DC-4A7E-AAA0-2BB0650C6A4BQ43243866-B1C8B4AB-D3C4-449F-944C-B0A491BC3B3DQ44752532-C186E1E2-D406-4FD2-AC48-44855EAFE958Q82563077-6DBD9198-2C11-422B-9B3F-FF862C908114Q83902378-C3011E79-1665-435B-8AD9-D550BE7C66B7
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Timo Rousu
@ast
Timo Rousu
@en
Timo Rousu
@es
Timo Rousu
@nl
Timo Rousu
@sl
type
label
Timo Rousu
@ast
Timo Rousu
@en
Timo Rousu
@es
Timo Rousu
@nl
Timo Rousu
@sl
prefLabel
Timo Rousu
@ast
Timo Rousu
@en
Timo Rousu
@es
Timo Rousu
@nl
Timo Rousu
@sl
P106
P21
P31
P496
0000-0002-9582-1279