Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
about
The human urine metabolomeExploring the utility of high-resolution MS with post-acquisition data mining for simultaneous exogenous and endogenous metabolite profiling.Post-acquisition analysis of untargeted accurate mass quadrupole time-of-flight MS(E) data for multiple collision-induced neutral losses and fragment ions of glutathione conjugates.Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometriesHigh-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.Simultaneous screening of glutathione and cyanide adducts using precursor ion and neutral loss scans-dependent product ion spectral acquisition and data mining tools.Improving mass defect filters for human proteins.Application of LC-high-resolution MS with 'intelligent' data mining tools for screening reactive drug metabolites.Detection and characterization of ticlopidine conjugates in rat bile using high-resolution mass spectrometry: applications of various data acquisition and processing tools.Profiling the reactive metabolites of xenobiotics using metabolomic technologiesOnline electrochemistry/mass spectrometry in drug metabolism studies: principles and applications.Revisiting the Metabolism and Bioactivation of Ketoconazole in Human and Mouse Using Liquid Chromatography-Mass Spectrometry-Based Metabolomics.Database searching for structural identification of metabolites in complex biofluids for mass spectrometry-based metabonomics.Drug metabolite profiling and identification by high-resolution mass spectrometry.Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS.The generation, detection, and effects of reactive drug metabolites.The current state-of-the-art in the determination of pharmaceutical residues in environmental matrices using hyphenated techniques.Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs.Biotransformation and bioactivation reactions - 2015 literature highlights.Mass-defect filtering of isotope signatures to reveal the source of chlorinated palm oil contaminants.Comparison of trapping profiles between d-peptides and glutathione in the identification of reactive metabolites.Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer.A tutorial in small molecule identification via electrospray ionization-mass spectrometry: The practical art of structural elucidation.Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences.
P2860
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P2860
Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@ast
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@en
type
label
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@ast
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@en
prefLabel
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@ast
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@en
P356
P1476
Rapid detection and characteri ...... e-of-flight mass spectrometry.
@en
P2093
Ari Tolonen
Olavi Pelkonen
P304
P356
10.1002/RCM.3953
P50
P577
2009-03-01T00:00:00Z