about
The role of MIZ-1 in MYC-dependent tumorigenesisGenetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoTIGAR is required for efficient intestinal regeneration and tumorigenesisMyc deletion rescues Apc deficiency in the small intestineRegulation of TFIIIB during F9 cell differentiation.Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancerA complex secretory program orchestrated by the inflammasome controls paracrine senescence.Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle ArrestActivation by c-Myc of transcription by RNA polymerases I, II and III.ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.Modulating the therapeutic response of tumours to dietary serine and glycine starvation.CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma.Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formationInactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinomaWnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers.Serine one-carbon catabolism with formate overflow.Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.The in vivo function of the p53 target gene TIGAR.In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability.RIPK3 promotes adenovirus type 5 activity.Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine.Increased formate overflow is a hallmark of oxidative cancer.RUNX1 is a driver of renal cell carcinoma correlating with clinical outcomeA Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic TestingFormate induces a metabolic switch in nucleotide and energy metabolism
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P50
description
hulumtues
@sq
onderzoeker
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researcher
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հետազոտող
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name
Dimitris Athineos
@ast
Dimitris Athineos
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Dimitris Athineos
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Dimitris Athineos
@nl
Dimitris Athineos
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type
label
Dimitris Athineos
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Dimitris Athineos
@en
Dimitris Athineos
@es
Dimitris Athineos
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Dimitris Athineos
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prefLabel
Dimitris Athineos
@ast
Dimitris Athineos
@en
Dimitris Athineos
@es
Dimitris Athineos
@nl
Dimitris Athineos
@sl
P106
P21
P31
P496
0000-0001-5298-7941