Myc deletion rescues Apc deficiency in the small intestine
about
A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult LiverTumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsMultiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loopsAn LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signalingThe ubiquitin-specific protease USP28 is required for MYC stabilityTrabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chainsAP4 encodes a c-MYC-inducible repressor of p21A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expressionWnt signaling: the good and the badManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerFrizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerRegulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancerMouse models of intestinal cancerColorectal cancer models for novel drug discoveryAdult mammalian stem cells: the role of Wnt, Lgr5 and R-spondinsThe role of MIZ-1 in MYC-dependent tumorigenesisMitotic and mitogenic Wnt signallingStrategies to achieve conditional gene mutation in miceTherapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesMouse models of colorectal cancer as preclinical modelsMicroRNA-26a promotes cholangiocarcinoma growth by activating β-cateninCDK8 is a colorectal cancer oncogene that regulates beta-catenin activityGenetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoDeficiency of Mbd2 attenuates Wnt signalingThe transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytesMYC on the path to cancerThe adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy.Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells.TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental programA limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapyThe function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells.Wnt-reporter expression pattern in the mouse intestine during homeostasis.c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland.Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.Regulation of TFIIIB during F9 cell differentiation.TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function.Stress-induced cleavage of Myc promotes cancer cell survival
P2860
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P2860
Myc deletion rescues Apc deficiency in the small intestine
description
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2007
@ast
scientific journal article
@en
vedecký článok (publikovaný 2007/04/05)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/04/05)
@nl
наукова стаття, опублікована у квітні 2007
@uk
مقالة علمية (نشرت في 5-4-2007)
@ar
name
Myc deletion rescues Apc deficiency in the small intestine
@ast
Myc deletion rescues Apc deficiency in the small intestine
@en
Myc deletion rescues Apc deficiency in the small intestine
@nl
type
label
Myc deletion rescues Apc deficiency in the small intestine
@ast
Myc deletion rescues Apc deficiency in the small intestine
@en
Myc deletion rescues Apc deficiency in the small intestine
@nl
prefLabel
Myc deletion rescues Apc deficiency in the small intestine
@ast
Myc deletion rescues Apc deficiency in the small intestine
@en
Myc deletion rescues Apc deficiency in the small intestine
@nl
P2093
P50
P3181
P356
P1433
P1476
Myc deletion rescues Apc deficiency in the small intestine
@en
P2093
Hans Clevers
J Keith Vass
Julie A Wilkins
Valerie S Meniel
Vanesa Muncan
P2888
P304
P3181
P356
10.1038/NATURE05674
P407
P577
2007-03-21T00:00:00Z
P5875
P6179
1002848303