Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeti
about
C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signalA novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitroCloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin familyMolecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type IPeroxisomal import of human alanine:glyoxylate aminotransferase requires ancillary targeting information remote from its C terminusPrimary hyperoxaluria type 1: a cluster of new mutations in exon 7 of the AGXT gene.Molecular Requirements for Peroxisomal Targeting of Alanine-Glyoxylate Aminotransferase as an Essential Determinant in Primary Hyperoxaluria Type 1Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p.Analysis of the carboxyl-terminal peroxisomal targeting signal 1 in a homologous context in Saccharomyces cerevisiae.Functional synergism between the most common polymorphism in human alanine:glyoxylate aminotransferase and four of the most common disease-causing mutationsMolecular etiology of primary hyperoxaluria type 1: new directions for treatmentRat pristanoyl-CoA oxidase. cDNA cloning and recognition of its C-terminal (SQL) by the peroxisomal-targeting signal 1 receptorEffect of protein structure on mitochondrial import.The glyoxysomal and plastid molecular chaperones (70-kDa heat shock protein) of watermelon cotyledons are encoded by a single geneMutants of the Yarrowia lipolytica PEX23 gene encoding an integral peroxisomal membrane peroxin mislocalize matrix proteins and accumulate vesicles containing peroxisomal matrix and membrane proteinsPrimary hyperoxaluria type 1 in the Canary Islands: a conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferaseStudies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase.Abnormality in catalase import into peroxisomes leads to severe neurological disorder.Targeting of human catalase to peroxisomes is dependent upon a novel COOH-terminal peroxisomal targeting sequence.Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele.Mitochondrial protein import and human health and disease.Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice.Role of peroxisomes in the biosynthesis and secretion of β-lactams and other secondary metabolites.Identification of peroxisomal targeting signal of pumpkin catalase and the binding analysis with PTS1 receptor.Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria.Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene.Molecular basis of the variable mitochondrial and peroxisomal localisation of alanine-glyoxylate aminotransferase.Components involved in peroxisome import, biogenesis, proliferation, turnover, and movement.The peroxisomal targeting sequence type 1 receptor, Pex5p, and the peroxisomal import efficiency of alanine:glyoxylate aminotransferase.A novel mutation of human liver alanine:glyoxylate aminotransferase causes primary hyperoxaluria type 1: immunohistochemical quantification and subcellular distribution.Correction of an enzyme trafficking defect in hereditary kidney stone disease in vitro.Pnc1 piggy-back import into peroxisomes relies on Gpd1 homodimerisation.Molecular adaptation of alanine:glyoxylate aminotransferase targeting in primates.Molecular basis for the dual mitochondrial and cytosolic localization of alanine:glyoxylate aminotransferase in amphibian liver cells.Caenorhabditis elegans has a single pathway to target matrix proteins to peroxisomes.Inhibition of alanine:glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1.Reconstruction of human hepatocyte glyoxylate metabolic pathways in stably transformed Chinese-hamster ovary cells.Mutational analyses of a type 2 peroxisomal targeting signal that is capable of directing oligomeric protein import into tobacco BY-2 glyoxysomes
P2860
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P2860
Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeti
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@en
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@nl
type
label
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@en
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@nl
prefLabel
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@en
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@nl
P2093
P2860
P356
P1476
Mammalian alanine/glyoxylate a ...... me-to-mitochondrion mistargeti
@en
P2093
Danpure CJ
De Zoysa PA
Jennings PR
Wanders RJ
P2860
P304
P356
10.1083/JCB.131.1.95
P407
P577
1995-10-01T00:00:00Z