Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation.
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Loss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiationSrc tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.Cux1 transcription factor is induced in inflammatory bowel disease and protects against experimental colitis.Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsCooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation.Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Intestinal mucosal atrophy and adaptationIntestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters.Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.Molecular mechanisms of Barrett's esophagus.Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networksHepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.Hepatocyte nuclear factor 4α suppresses the aggravation of colon carcinoma.Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa.Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.Hepatocyte Nuclear Factor 4α Regulates the Expression of Intestinal Epithelial Na(+)/H(+) Exchanger Isoform-3 (NHE3).Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.Association between genetic variants in the HNF4A gene and childhood-onset Crohn's disease.Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.IBD candidate genes and intestinal barrier regulation.FABP1 knockdown in human enterocytes impairs proliferation and alters lipid metabolism.Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation.
P2860
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P2860
Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@en
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@nl
type
label
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@en
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@nl
prefLabel
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@en
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@nl
P2093
P2860
P356
P1476
Hepatocyte nuclear factor 4alp ...... al epithelium differentiation.
@en
P2093
Carine R Lussier
François Boudreau
Jean-Philippe Babeu
Mathieu Darsigny
P2860
P304
P356
10.1152/AJPGI.90690.2008
P577
2009-04-23T00:00:00Z