Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling. - Wikidata - wikimedia - TriplyDB

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

http://www.wikidata.org/entity/Q42801075

about

Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies Ron-receptor tyrosine kinase in tumorigenesis and metastasis Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.Ubiquitination-dependent regulation of signaling receptors in cancer.Degradation of activated protein kinases by ubiquitination.Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.Role of Recepteur D'origine Nantais on Gastric Cancer Development and Progression Heat shock factor 1 deficiency via its downstream target gene alphaB-crystallin (Hspb5) impairs p53 degradation.Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation.RON Signaling Is a Key Mediator of Tumor Progression in Many Human Cancers.

P2860

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P2860

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

http://www.wikidata.org/entity/Q42801075

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

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2006年论文

@zh

2006年论文

@zh-cn

name

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@en

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@nl

type

label

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@en

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@nl

prefLabel

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@en

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling

@en

P2093

Ami Citri

http://www.w3.org/2001/XMLSchema#string

Davide Barberis

http://www.w3.org/2001/XMLSchema#string

Giovanni Gaudino

http://www.w3.org/2001/XMLSchema#string

Lorenza Penengo

http://www.w3.org/2001/XMLSchema#string

Serena Germano

http://www.w3.org/2001/XMLSchema#string

Yosef Yarden

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

Identification of the ron gene product as the receptor for the human macrophage stimulating protein

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

A system for stable expression of short interfering RNAs in mammalian cells

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

Oncogenic kinase signalling

Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential

ErbB2 degradation mediated by the co-chaperone protein CHIP

P304

21710-21719

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P31

scholarly article

P356

10.1074/JBC.M602014200

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31

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P478

281

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Massimo M Santoro

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2006-06-01T00:00:00Z

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P5875

7041598

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16740632

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