Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
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Global profiling of dynamic protein palmitoylation2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activitiesAcyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43Ras plasma membrane signalling platformsRaft protein clustering alters N-Ras membrane interactions and activation pattern.Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signalingTandem fluorescence imaging of dynamic S-acylation and protein turnover.Palmitoylation of SARS-CoV S protein is necessary for partitioning into detergent-resistant membranes and cell-cell fusion but not interaction with M protein.Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis.Compartment-specific feedback loop and regulated trafficking can result in sustained activation of Ras at the Golgi.Palmitoylation-dependent protein sorting.Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation.Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane.Protein palmitoylation inhibition by 2-bromopalmitate alters gliding, host cell invasion and parasite morphology in Toxoplasma gondiiA New View of Ras Isoforms in Cancers.Protein palmitoylation and pathogenesis in apicomplexan parasites.Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway.Nonconventional trafficking of Ras associated with Ras signal organization.Profiling and inhibiting reversible palmitoylationRas proteins: paradigms for compartmentalised and isoform-specific signalling.Ras nanoclusters: molecular structure and assemblyChemical approaches for profiling dynamic palmitoylationFat chance! Getting a grip on a slippery modification.Ras acylation, compartmentalization and signaling nanoclusters (Review).Protein acyl thioesterases (Review).Compartmentalized signalling: Ras proteins and signalling nanoclusters.Progress toward Understanding Protein S-acylation: Prospective in PlantsRegulating the regulator: post-translational modification of RASApproaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).Targeting protein palmitoylation: selective inhibitors and implications in disease.Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events.Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling.K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes.Subcellular Distribution of S-Nitrosylated H-Ras in Differentiated and Undifferentiated PC12 Cells during Hypoxia.Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii.Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading.FKBP12 binds to acylated H-ras and promotes depalmitoylation.
P2860
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P2860
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@en
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@nl
type
label
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@en
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@nl
prefLabel
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@en
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@nl
P2093
P2860
P356
P1476
Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.
@en
P2093
Janice E Buss
Jonathan L Coloff
Joy Walker
Tara L Baker
P2860
P304
19292-19300
P356
10.1074/JBC.M206956200
P407
P577
2003-03-17T00:00:00Z