Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.
about
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitPhosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulationTyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transductionThe SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytesActivation of Src family kinases by colony stimulating factor-1, and their association with its receptorA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinaseDiabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activityPhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoIdentification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirusExpression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression systemPurification and characterization of human erythrocyte phosphatidylinositol 4-kinase. Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase are distinct enzymesMultiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translationAutophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoAssociation of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activityAssociation of protein phosphatase 2A with polyoma virus medium tumor antigenCloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphataseInteractions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorMolecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa proteinHuman Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulatorGenetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificityRetroviral oncogenes: a historical primerDirect association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 betaCloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85The PI3K pathway as drug target in human cancerAn Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinasesThe structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinaseLipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathwayProtein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytescDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinaseShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexesWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionG-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptorSpecific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and VavA Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling.Regulation of PI3K/Akt dependent apoptotic markers during b virus infection of human and macaque fibroblasts.Cooperation of Src homology domains in the regulated binding of phosphatidylinositol 3-kinase. A role for the Src homology 2 domain.Phosphatidylinositol 3-kinase activity is important for progesterone-induced Xenopus oocyte maturation.
P2860
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P2860
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Common elements in growth fact ...... tidylinositol kinase activity.
@en
Common elements in growth fact ...... tidylinositol kinase activity.
@nl
type
label
Common elements in growth fact ...... tidylinositol kinase activity.
@en
Common elements in growth fact ...... tidylinositol kinase activity.
@nl
prefLabel
Common elements in growth fact ...... tidylinositol kinase activity.
@en
Common elements in growth fact ...... tidylinositol kinase activity.
@nl
P2093
P1433
P1476
Common elements in growth fact ...... tidylinositol kinase activity.
@en
P2093
B Schaffhausen
D C Pallas
D R Kaplan
T M Roberts
P304
P356
10.1016/0092-8674(87)90168-1
P407
P577
1987-09-01T00:00:00Z