Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
about
K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and functionK-Ras protein as a drug targetRas plasma membrane signalling platformsRas, an actor on many stages: posttranslational modifications, localization, and site-specified events.Both the C-terminal polylysine region and the farnesylation of K-RasB are important for its specific interaction with calmodulinDifferential Regulation of RasGAPs in Cancer.Control of Ras cycling by Ca2+.The hypervariable region of K-Ras4B is responsible for its specific interactions with calmodulinCalmodulin-mediated regulation of the epidermal growth factor receptor.Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?Modeling of RAS complexes supports roles in cancer for less studied partners.Flexible-body motions of calmodulin and the farnesylated hypervariable region yield a high-affinity interaction enabling K-Ras4B membrane extraction.Growth factor-dependent AKT activation and cell migration requires the function of c-K(B)-Ras versus other cellular ras isoforms.Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors.Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation.Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts.CaM interaction and Ser181 phosphorylation as new K-Ras signaling modulators.Identification of essential interacting elements in K-Ras/calmodulin binding and its role in K-Ras localization.Application of reductive ¹³C-methylation of lysines to enhance the sensitivity of conventional NMR methods.Sodium tungstate activates glycogen synthesis through a non-canonical mechanism involving G-proteins.Sasanquasaponin up-regulates anion exchanger 3 expression and elicits cardioprotection via NO/RAS/ERK1/2 pathway.
P2860
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P2860
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@en
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@nl
type
label
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@en
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@nl
prefLabel
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@en
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@nl
P2093
P2860
P50
P356
P1476
Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts.
@en
P2093
Antonio Chiloeches
Cristina López-Alcalá
Oriol Bachs
P2860
P304
37929-37935
P356
10.1074/JBC.M202245200
P407
P577
2002-07-31T00:00:00Z