Effects of TCF7L2 polymorphisms on obesity in European populations.
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Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetesPolymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic RTCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liverTCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention programStratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysisNo association between a candidate TCF7L2 variant and risk of breast or ovarian cancer.Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes.Transcription factor 7-like 2 polymorphism and context-specific risk of metabolic syndrome, type 2 diabetes, and dyslipidemia.Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study.Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes.Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humansThe T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest.Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study.The emerging genetic architecture of type 2 diabetesAssociation between the rs12255372 variant of the TCF7L2 gene and obesity in a Cameroonian population.TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study.TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weight-loss interventionGenetic variants associated with lean and obese type 2 diabetes in a Han Chinese population: A case-control study.Association of TCF7L2 and ADIPOQ with body mass index, waist-hip ratio, and systolic blood pressure in an endogamous ethnic group of India.Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia.A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistanceRole of the single nucleotide polymorphism rs7903146 of TCF7L2 in inducing nonsense-mediated decay.Association analyses between type 2 diabetes genes and obesity traits in pigs.Evidence for an influence of TCF7L2 polymorphism rs7903146 on insulin resistance and sensitivity indices in overweight children and adolescents during a lifestyle intervention.Glucose tolerance and free fatty acid metabolism in adults with variations in TCF7L2 rs7903146.Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method.Associations of common variants in the SLC16A11, TCF7L2, and ABCA1 genes with pediatric-onset type 2 diabetes and related glycemic traits in families: A case-control and case-parent trio study.
P2860
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P2860
Effects of TCF7L2 polymorphisms on obesity in European populations.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Effects of TCF7L2 polymorphisms on obesity in European populations.
@en
Effects of TCF7L2 polymorphisms on obesity in European populations.
@nl
type
label
Effects of TCF7L2 polymorphisms on obesity in European populations.
@en
Effects of TCF7L2 polymorphisms on obesity in European populations.
@nl
prefLabel
Effects of TCF7L2 polymorphisms on obesity in European populations.
@en
Effects of TCF7L2 polymorphisms on obesity in European populations.
@nl
P2093
P2860
P50
P356
P1433
P1476
Effects of TCF7L2 polymorphisms on obesity in European populations.
@en
P2093
Alex Duval
Beverley Balkau
Christian Dina
Christine Proença
David Meyre
Fritz Horber
Frédéric Capel
Guillaume Charpentier
Katrine Grau
Natascha Potoczna
P2860
P304
P356
10.1038/OBY.2007.77
P577
2008-02-01T00:00:00Z