Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is dependent upon both the amino terminus and the large cytoplasmic loop.
about
GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocationThe glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytesp115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocationHigh basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes.The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesiclesMetabolic syndrome and insulin resistance: underlying causes and modification by exercise training.Single point mutations result in the miss-sorting of Glut4 to a novel membrane compartment associated with stress granule proteins.Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocationThe glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner.Biogenesis and regulation of insulin-responsive vesicles containing GLUT4.A proteolytic pathway that controls glucose uptake in fat and muscle.Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors.Initial entry of IRAP into the insulin-responsive storage compartment occurs prior to basal or insulin-stimulated plasma membrane recycling.Adipocytes support cAMP-dependent translocation of aquaporin-2 from intracellular sites distinct from the insulin-responsive GLUT4 storage compartment.A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment.The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles.
P2860
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P2860
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is dependent upon both the amino terminus and the large cytoplasmic loop.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@en
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@nl
type
label
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@en
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@nl
prefLabel
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@en
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@nl
P2093
P2860
P356
P1476
Entry of newly synthesized GLU ...... nd the large cytoplasmic loop.
@en
P2093
Ahmir H Khan
Jeffery R Smith
Jeffrey E Pessin
June Chunqiu Hou
Robert T Watson
P2860
P304
37505-37511
P356
10.1074/JBC.M405694200
P407
P577
2004-07-07T00:00:00Z