Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.
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SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase Cp110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytesPhosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking proteinInteraction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in bindingMembrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationThe 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphataseAkt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptorExpression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexesNew targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonistsPTEN regulation of ERK1/2 signaling in cancerPhosphoinositides: tiny lipids with giant impact on cell regulationIdentification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinaseCharacterization of S6K2, a novel kinase homologous to S6K1Loss of PTEN facilitates HIF-1-mediated gene expressionTC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathwayLPA stimulates intestinal DRA gene transcription via LPA2 receptor, PI3K/AKT, and c-Fos-dependent pathwayPhosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signalingPhosphoinositide 3-kinase-gamma induces Xenopus oocyte maturation via lipid kinase activityRegulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunitERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neuronsThe insulin-like growth factor 1 receptor is essential for axonal regeneration in adult central nervous system neuronsARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathwayUpregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cellsPhosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling moleculesRole of platelet-derived growth factors in physiology and medicineThe lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains.Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association.Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain.Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase.Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.Interaction of neurotrophin signaling with Bcl-2 localized to the mitochondria and endoplasmic reticulum on spiral ganglion neuron survival and neurite growthThe ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos.N-methyl D-aspartate receptor-mediated bidirectional control of extracellular signal-regulated kinase activity in cortical neuronal cultures.
P2860
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P2860
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@en
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@nl
type
label
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@en
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@nl
prefLabel
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@en
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@nl
P2093
P356
P1433
P1476
Ras-dependent induction of cel ...... phosphatidylinositol-3 kinase.
@en
P2093
P304
P356
10.1126/SCIENCE.7701328
P407
P577
1995-04-01T00:00:00Z