Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.
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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to RhoDistinct carboxy-termini confer divergent characteristics to the mitogen-activated protein kinase p38alpha and its splice isoform Mxi2Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivativeMuscarinic acetylcholine receptors activate expression of the EGR gene family of transcription factorsMultiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformationActivation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinaseIncreased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activationRegulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptorscbl-b inhibits epidermal growth factor receptor signalingThe human histamine H(2) receptor regulates c-jun and c-fos in a differential mannerDirect interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factorjkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegansBile acid stimulation of early growth response gene and mitogen-activated protein kinase is protein kinase C-dependentCrk activation of JNK via C3G and R-RasIntegrin function: molecular hierarchies of cytoskeletal and signaling moleculesSignaling events following chemokine receptor ligation in human dendritic cells at different developmental stages.JNK, cytoskeletal regulator and stress response kinase? A Drosophila perspective.A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation.Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases.The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro.Stress-activated protein kinases are negatively regulated by cell density.Rho GTPase-dependent transformation by G protein-coupled receptors.Modulation of DNA synthesis by muscarinic cholinergic receptors.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation.Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinasesPhosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced by platelet-derived growth factor.Dehydroepiandrosterone Sulfate Stimulates Expression of Blood-Testis-Barrier Proteins Claudin-3 and -5 and Tight Junction Formation via a Gnα11-Coupled Receptor in Sertoli Cells.Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells.Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle.Vav regulates peptide-specific apoptosis in thymocytesGTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases.Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis.The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.G protein regulation of MAPK networks.MAP kinases and the control of nuclear events.rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase.
P2860
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P2860
Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Transforming G protein-coupled ...... sine kinase signaling pathway.
@en
Transforming G protein-coupled receptors potently activate JNK
@nl
type
label
Transforming G protein-coupled ...... sine kinase signaling pathway.
@en
Transforming G protein-coupled receptors potently activate JNK
@nl
prefLabel
Transforming G protein-coupled ...... sine kinase signaling pathway.
@en
Transforming G protein-coupled receptors potently activate JNK
@nl
P2093
P2860
P356
P1476
Transforming G protein-coupled ...... osine kinase signaling pathway
@en
P2093
J M Kyriakis
J Woodgett
M Chiariello
P2860
P304
P356
10.1074/JBC.270.10.5620
P407
P577
1995-03-01T00:00:00Z