rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase.
about
RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitorsRhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damageGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoThe C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathwayRhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cellsRhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.Ras-related GTPase Rhob represses NF-kappaB signaling.RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasisFarnesyltransferase inhibitors: mechanism and applications.RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblastsSimultaneous irradiation of fibroblasts and carcinoma cells repress the secretion of soluble factors able to stimulate carcinoma cell migration.Pathway-specific effect of caffeine on protection against UV irradiation-induced apoptosis in corneal epithelial cells.The c-Jun/RHOB/AKT pathway confers resistance of BRAF-mutant melanoma cells to MAPK inhibitors.ROCK I-mediated activation of NF-kappaB by RhoBDedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase.RhoB regulates the function of macrophages in the hypoxia-induced inflammatory response.Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element.Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line.Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal.Induction of small G protein RhoB by non-genotoxic stress inhibits apoptosis and activates NF-κB.MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling.Difference in the cytotoxic effects of toxin B from Clostridium difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470.Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation.The role of PI 3-kinase in the UVB-induced expression of c-fos.Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells.Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.Progesterone Inhibits Endothelial Cell Migration Through Suppression of the Rho Activity Mediated by cSrc Activation.RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.Mitogen-responsive expression of RhoB is regulated by RNA stability.Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway.Cytoprotective effect of the small GTPase RhoB expressed upon treatment of fibroblasts with the Ras-glucosylating Clostridium sordellii lethal toxin.Regulation of cGMP-dependent protein kinase expression by Rho and Kruppel-like transcription factor-4.RhoB: Team Oncogene or Team Tumor Suppressor?Parallels between single cell migration and barrier formation: The case of RhoB and Rac1 trafficking.
P2860
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P2860
rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
rhoB encoding a UV-inducible R ...... JNK, ERK, and p38 MAP kinase.
@en
type
label
rhoB encoding a UV-inducible R ...... JNK, ERK, and p38 MAP kinase.
@en
prefLabel
rhoB encoding a UV-inducible R ...... JNK, ERK, and p38 MAP kinase.
@en
P2860
P356
P1476
rhoB encoding a UV-inducible R ...... JNK, ERK, and p38 MAP kinase.
@en
P2860
P304
30637-30644
P356
10.1074/JBC.272.49.30637
P407
P577
1997-12-01T00:00:00Z