Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase.
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The role of oxidative stress in Parkinson's diseaseThe power to reduce: pyridine nucleotides--small molecules with a multitude of functionsInflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's DiseaseMitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modificationsDiabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stressCrystal structure of porcine mitochondrial NADP+-dependent isocitrate dehydrogenase complexed with Mn2+ and isocitrate. Insights into the enzyme mechanismStructural studies ofSaccharomyces cerevesiaemitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reactionKinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases.A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiaeTwo sources of mitochondrial NADPH in the yeast Saccharomyces cerevisiae.Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic NephropathyStructures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activityIsocitrate dehydrogenase from Streptococcus mutans: biochemical properties and evaluation of a putative phosphorylation site at Ser102Early mitochondrial dysfunction in long-lived Mclk1+/- miceDual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeastSirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restrictionA novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network.Molecular mechanism of the allosteric regulation of the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase.A proteomics study of the response of North Ronaldsay sheep to copper challengeCytosolic NADP-isocitrate dehydrogenase of pea plants: genomic clone characterization and functional analysis under abiotic stress conditions.Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth.Increased susceptibility of IDH2-deficient mice to dextran sodium sulfate-induced colitis.Heteroexpression and characterization of a monomeric isocitrate dehydrogenase from the multicellular prokaryote Streptomyces avermitilis MA-4680.Alveolate mitochondrial metabolic evolution: dinoflagellates force reassessment of the role of parasitism as a driver of change in apicomplexans.Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease.Experimental verification and molecular basis of active immunization against fungal pathogens in termites.Biochemical characterization of NADP⁺-dependent isocitrate dehydrogenase from Microcystis aeruginosa PCC7806.Enzyme redundancy and the importance of 2-oxoglutarate in plant ammonium assimilation.Alcohol and mitochondria: a dysfunctional relationshipDisruption of pyridine nucleotide redox status during oxidative challenge at normal and low-glucose states: implications for cellular adenosine triphosphate, mitochondrial respiratory activity, and reducing capacity in colon epithelial cellsA role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Novel type II and monomeric NAD+ specific isocitrate dehydrogenases: phylogenetic affinity, enzymatic characterization, and evolutionary implication.Distinct metabolomic signatures are associated with longevity in humans.SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis.Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolismOxidative stress evokes a metabolic adaptation that favors increased NADPH synthesis and decreased NADH production in Pseudomonas fluorescensLoss of SIRT3 Provides Growth Advantage for B Cell Malignancies.Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease.Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
P2860
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P2860
Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@en
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@nl
type
label
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@en
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@nl
prefLabel
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@en
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@nl
P2093
P356
P1476
Control of mitochondrial redox ...... dent isocitrate dehydrogenase.
@en
P2093
P304
16168-16176
P356
10.1074/JBC.M010120200
P407
P577
2001-02-13T00:00:00Z