A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation.
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The association of cortactin with profilin-1 is critical for smooth muscle contractionABL tyrosine kinases: evolution of function, regulation, and specificityMass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cellsAbelson phosphorylation of CLASP2 modulates its association with microtubules and actinRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsCortactin branches out: roles in regulating protrusive actin dynamicsMultifunctional Abl kinases in health and diseaseCortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistenceCortactin as a target for FAK in the regulation of focal adhesion dynamicsTwo Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated CortactinAbl2/Arg controls dendritic spine and dendrite arbor stability via distinct cytoskeletal control pathwaysCortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturationArg interacts with cortactin to promote adhesion-dependent cell edge protrusionc-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesisβ1 integrins regulate fibroblast chemotaxis through control of N-WASP stability.Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulationCortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp.The c-Abl tyrosine kinase regulates actin remodeling at the immune synapseCortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin.Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier functionSrc regulates sequence-dependent beta-2 adrenergic receptor recycling via cortactin phosphorylation.Protein kinase substrate identification on functional protein arraysRNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry.Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemiaDeubiquitylase, deSUMOylase, and deISGylase activity microarrays for assay of substrate preference and functional modifiersc-Abl tyrosine kinase regulates cytokinesis of human airway smooth muscle cells.Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia FunctionCortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading.Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.Abl kinases are required for invadopodia formation and chemokine-induced invasion.An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac.Cortactin: a multifunctional regulator of cellular invasivenessAbl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.Targeting Abl kinases to regulate vascular leak during sepsis and acute respiratory distress syndrome.The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamicsActivation of abl family kinases in solid tumors.
P2860
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P2860
A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A critical role for cortactin ...... induced dorsal-wave formation.
@en
A critical role for cortactin ...... induced dorsal-wave formation.
@nl
type
label
A critical role for cortactin ...... induced dorsal-wave formation.
@en
A critical role for cortactin ...... induced dorsal-wave formation.
@nl
prefLabel
A critical role for cortactin ...... induced dorsal-wave formation.
@en
A critical role for cortactin ...... induced dorsal-wave formation.
@nl
P2093
P1433
P1476
A critical role for cortactin ...... induced dorsal-wave formation.
@en
P2093
Anthony J Koleske
Barry Schweitzer
Gregory A Michaud
Paul F Predki
Scott N Boyle
P304
P356
10.1016/J.CUB.2007.01.057
P407
P577
2007-02-15T00:00:00Z