about
Structural basis for androgen specificity and oestrogen synthesis in human aromataseThe genetic and functional basis of isolated 17,20-lyase deficiencySome rewarding effects of androgens may be mediated by actions of its 5alpha-reduced metabolite 3alpha-androstanediolThe planetary biology of cytochrome P450 aromatasesThe genomic environment around the Aromatase gene: evolutionary insightsNovel Aromatase Inhibitors by Structure-Guided DesignMolecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis studyCharacterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 geneCatalytic differences between porcine blastocyst and placental aromatase isozymes.Evaluation of the mechanism of aromatase cytochrome P450. A site-directed mutagenesis study.X-ray structure of human aromatase reveals an androgen-specific active siteSingle-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks.Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation.Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development.Nonsteroidal aromatase inhibitors: recent advances.A case of Aromatase deficiency due to a novel CYP19A1 mutation.Oleic acid metabolism via a conserved cytochrome P450 system-mediated ω-hydroxylation in the bark beetle-associated fungus Grosmannia clavigera.Incorporation of charged residues in the CYP2J2 F-G loop disrupts CYP2J2-lipid bilayer interactions.Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase.Expression and sequence evolution of aromatase cyp19a1 and other sexual development genes in East African cichlid fishesOrganization of cytochrome P450 enzymes involved in sex steroid synthesis: PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES.Computational methods for the design of potent aromatase inhibitors.Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes.Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.Study of substrate specificity of human aromatase by site directed mutagenesis.Membrane binding and substrate access merge in cytochrome P450 7A1, a key enzyme in degradation of cholesterol.Membrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1.Membrane integration of recombinant human P450 forms.The use of computational chemistry in the study of sex steroid biosynthesis.Aromatase deficiency owing to a functional variant in the placenta promoter and a novel missense mutation in the CYP19A1 gene.Three-dimensional model of cytochrome P450 human aromatase.Gene structure and comparative and phylogenetic analyses of Catla catla CYP1A full-length cDNA and its responsiveness to benzo(a)pyrene and copper sulphate at early developmental stages.Molecular Cloning and Characterization of Carotenoid Pathway Genes and Carotenoid Content in Ixeris dentata var. albiflora.Memetic algorithms for ligand expulsion from protein cavities.Female pseudohermaphroditism associated with a novel homozygous G-to-A (V370-to-M) substitution in the P-450 aromatase gene.Automated multiple analysis of protein structures: application to homology modeling of cytochromes P450.Synthesis and evaluation of benzoxazolinonic imidazoles and derivatives as non-steroidal aromatase inhibitors.Differential expression of two distinct aromatase genes (cyp19a1aandcyp19a1b) during vitellogenesis and gestation in the viviparous black rockfishSebastes schlegelii
P2860
Q24314572-19956BE8-AB1A-4484-A3A3-4607079D3638Q24317633-D3DBA24E-04B8-4BF7-8611-8372B6C04915Q24679317-82442FBC-E267-4F8F-B62D-0B1B6A96B768Q24804422-FDBCB00C-5BB5-4B38-B475-16BC3D767A8EQ24814591-5C74DBDA-9633-4EC3-9A6E-969083AD1018Q27672328-01725F07-D611-42CC-8EDC-1CB84A0134B3Q28379302-7CDAF6BC-EF00-4CB9-A73B-0B771BF82149Q28588388-F99DC2DD-9351-4A53-83E9-717A1A6ED4CAQ31442512-C3F143A6-A3E2-4669-A63E-6A6A9DDDB646Q31895320-23ED0EE4-5C0E-4203-AEBA-97B3EDBEBB91Q33679045-505644AD-668C-45C7-B54F-0B2843237432Q34067351-9076FB6B-946E-464F-8B36-C5D2BE6D27B4Q34546874-09B82013-70A5-4B74-AE12-70D4473F6A2DQ34561176-AAC43F8A-A2B6-42E1-ADCF-43B89E74892EQ34587518-9DDD55E5-A0C1-47FE-8993-4410E2A2DE26Q35098201-26B4B6C0-90F0-4A69-BE7B-E982F3343955Q35201768-AF21ACDB-4CD3-4FE9-8A8F-B0EC4E755A92Q36025678-568B5AA2-5E1C-40E4-A2D6-5A7387ACECA8Q37025619-E37A535B-3E81-4B58-B4D5-AC5250002D35Q37102311-96EBB4BC-B90E-4E0B-8459-304FA6E83A52Q37171771-A6D2A1FE-9761-4E8C-8DB8-D691C7A7A358Q37446094-C907331F-8CC8-4BD4-89BE-54BB128E73E4Q38078417-56ED67C1-CA10-49FE-AC42-5A68F3A66D52Q41569993-86C08DF2-3861-4D75-93CE-3836BD2B745DQ42280424-CCECFBEF-F4B9-40F3-BDAA-44F771D780E0Q42671302-DDF8B260-C980-44C9-BE90-7A3D53F11AB3Q43651964-1B341593-44AD-4C5B-90F6-6D32880477ACQ44068667-F6CFC300-6844-4B89-99B1-586EE81ABAD1Q45965531-B9A0E298-22A2-45CA-B9B6-0E05B190B076Q46152153-0D293186-44AF-4E58-A9B8-D52F838AB7D7Q46834008-786250AE-0A0F-465D-A139-7647C4B1D6C0Q46891612-5D023247-AB9D-486E-A9CB-4A009DDCD165Q48148505-0683E059-EC45-4FB9-A75A-8D2D2AFC673EQ50247065-393AC6CF-2852-452B-ACF8-019CDB4AC07FQ50557737-C1CB4D5B-AFF0-4A72-92B4-DDFFED4D8415Q50855894-618CE59A-14AC-47BE-95A6-2DB24DB2E0EDQ52261420-73A72F04-96E1-4DB7-A03E-1FC4667C3966Q53633839-95346911-2429-4844-8A45-80D0E573A101Q58282465-F86520BC-BF5C-41F3-AEBC-31D1AB449382
P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
A three-dimensional model of aromatase cytochrome P450.
@en
A three-dimensional model of aromatase cytochrome P450.
@nl
type
label
A three-dimensional model of aromatase cytochrome P450.
@en
A three-dimensional model of aromatase cytochrome P450.
@nl
prefLabel
A three-dimensional model of aromatase cytochrome P450.
@en
A three-dimensional model of aromatase cytochrome P450.
@nl
P2093
P2860
P356
P1433
P1476
A three-dimensional model of aromatase cytochrome P450.
@en
P2093
E R Simpson
J A Peterson
S Graham-Lorence
P2860
P304
P356
10.1002/PRO.5560040605
P577
1995-06-01T00:00:00Z