Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family.
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A novel adaptation of the integrin PSI domain revealed from its crystal structureDefective discoidin domain structure, subunit assembly, and endoplasmic reticulum processing of retinoschisin are primary mechanisms responsible for X-linked retinoschisisDiscovery of platyhelminth-specific α/β-integrin families and evidence for their role in reproduction in Schistosoma mansoniProtein structure prediction and biomolecular recognition: from protein sequence to peptidomimetic design with the human beta3 integrin.The N-terminal region and the mid-region complex of the integrin beta 2 subunit.Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).A minimized human integrin alpha(5)beta(1) that retains ligand recognition.Glanzmann thrombasthenia: state of the art and future directions.Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits.Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P- and E-selectin.Platelet integrin alphaIIbbeta3-ligand interactions: what can we learn from the structure?A single disulfide bond disruption in the β3 integrin subunit promotes thiol/disulfide exchange, a molecular dynamics study.Insights into integrin-ligand binding and activation from the first crystal structure.Glanzmann's thrombasthenia: an overview.Molecular dynamics analysis of a novel β3 Pro189Ser mutation in a patient with glanzmann thrombasthenia differentially affecting αIIbβ3 and αvβ3 expression.Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeuticsAn amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen systemFolding of the conserved domain but not of flanking regions in the integrin beta2 subunit requires association with the alpha subunitStructure/function analysis of the integrin beta 1 subunit by epitope mapping.Modeling the alpha IIb beta 3 integrin solution conformation.Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection.Immunoregulation through membrane proteins modified by reducing conditions induced by immune reactions.Identification and characterization of two cation binding sites in the integrin beta 3 subunit.Inhibition of Protein Disulfide Isomerase in Thrombosis.High-efficiency utilization of the bovine integrin alpha(v)beta(3) as a receptor for foot-and-mouth disease virus is dependent on the bovine beta(3) subunit.Specific cysteines in beta3 are involved in disulfide bond exchange-dependent and -independent activation of alphaIIbbeta3.Interaction and functional association of protein disulfide isomerase with alphaVbeta3 integrin on endothelial cells.Adhesion molecules and their role in cancer metastasis.Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation.Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain.Identification of a region in the integrin beta3 subunit that confers ligand binding specificity.A novel activating anti-beta1 integrin monoclonal antibody binds to the cysteine-rich repeats in the beta1 chain.Activation of the integrin alpha v beta 3 involves a discrete cation-binding site that regulates conformation.Ligand binding and affinity modulation of integrins.Three-dimensional model of human platelet integrin alphaIIb beta3 in solution obtained by small angle neutron scattering.Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3).Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit.Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit.Novel Mutations in the GPIIb and GPIIIa Genes in Glanzmann Thrombasthenia.Proteolytic dissection of the isolated platelet fibrinogen receptor, integrin GPIIb/IIIa. Localization of GPIIb and GPIIIa sequences putatively involved in the subunit interface and in intrasubunit and intrachain contacts.
P2860
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P2860
Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Assignment of disulphide bonds ...... bunits of the integrin family.
@en
Assignment of disulphide bonds ...... bunits of the integrin family.
@nl
type
label
Assignment of disulphide bonds ...... bunits of the integrin family.
@en
Assignment of disulphide bonds ...... bunits of the integrin family.
@nl
prefLabel
Assignment of disulphide bonds ...... bunits of the integrin family.
@en
Assignment of disulphide bonds ...... bunits of the integrin family.
@nl
P2860
P356
P1433
P1476
Assignment of disulphide bonds ...... bunits of the integrin family.
@en
P2093
González-Rodríguez J
Henschen A
P2860
P356
10.1042/BJ2740063
P407
P478
274 ( Pt 1)
P577
1991-02-01T00:00:00Z