Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice. - Wikidata - wikimedia - TriplyDB

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice.

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice.

http://www.wikidata.org/entity/Q42870334

about

G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs Transnasal delivery of human A-beta peptides elicits impaired learning and memory performance in wild type mice.Pituitary adenylate cyclase-activating polypeptide is reduced in Alzheimer disease.Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases.Induction of RAGE shedding by activation of G protein-coupled receptors.Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells.Emerging Insights for Translational Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Studies: Towards Prediction of Nose-to-Brain Transport in Humans Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons Intranasal Delivery of Proteins and Peptides in the Treatment of Neurodegenerative Diseases Stimulation of synthesis and release of brain-derived neurotropic factor from intestinal smooth muscle cells by substance P and pituitary adenylate cyclase-activating peptide Coordination between proteasome impairment and caspase activation leading to TAU pathology: neuroprotection by cAMP.Somatostatinergic systems: an update on brain functions in normal and pathological aging.Inhibition of microRNA-210 provides neuroprotection in hypoxic-ischemic brain injury in neonatal rats.Alternative Splicing of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor PAC1: Mechanisms of Fine Tuning of Brain Activity.Regulating the ubiquitin/proteasome pathway via cAMP-signaling: neuroprotective potential PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis Nanotechnology for CNS delivery of bio-therapeutic agents.PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells Therapeutic potential of PACAP for neurodegenerative diseases.PACAP protects against inflammatory-mediated toxicity in dopaminergic SH-SY5Y cells: implication for Parkinson's disease.Crosstalk between angiotensin and the nonamyloidogenic pathway of Alzheimer's amyloid precursor protein.Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα.PACAP protects against salsolinol-induced toxicity in dopaminergic SH-SY5Y cells: implication for Parkinson's disease.Pituitary Adenylate Cyclase Activating Polypeptide, A Potential Therapeutic Agent for Diabetic Retinopathy in Rats: Focus on the Vertical Information Processing Pathway.Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.Genome-wide discovery of long intergenic noncoding RNAs and their epigenetic signatures in the rat.Pituitary adenylate cyclase-activating polypeptide (PACAP) protects against mitoxantrone-induced cardiac injury in mice.Pituitary adenylate cyclase-activating polypeptide receptors in the trigeminovascular system: implications for migraine.Association of pituitary adenylate cyclase-activating polypeptide with cognitive decline in mild cognitive impairment due to Alzheimer disease.Tackling dipeptidyl peptidase IV in neurological disorders.Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review

P2860

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P2860

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice.

http://www.wikidata.org/entity/Q42870334

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Neuropeptide pituitary adenyla ...... ursor protein-transgenic mice.

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Neuropeptide pituitary adenylate cyclase-activating polypeptide

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type

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Neuropeptide pituitary adenyla ...... ursor protein-transgenic mice.

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Neuropeptide pituitary adenylate cyclase-activating polypeptide

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prefLabel

Neuropeptide pituitary adenyla ...... ursor protein-transgenic mice.

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Neuropeptide pituitary adenylate cyclase-activating polypeptide

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Neuropeptide pituitary adenyla ...... ursor protein-transgenic mice.

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Clara Theunis

http://www.w3.org/2001/XMLSchema#string

Dorothea Rat

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Elzbieta Kojro

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Ewa Wieczerzak

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Falk Fahrenholz

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Frank Tippmann

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Fred van Leuven

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Ilse Dewachter

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Rolf Postina

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Ulrich Schmitt

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P2860

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB

The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein

Differential signal transduction by five splice variants of the PACAP receptor

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit nuclear factor-kappa B-dependent gene activation at multiple levels in the human monocytic cell line THP-1.

Pulmonary and systemic effects of inhaled PACAP38 in healthy male subjects.

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3208-3218

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10.1096/FJ.10-180133

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9

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25

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51147460

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21593432

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Alzheimer's disease

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3157688

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