Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.
about
MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sitesDifferential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutationAltered pattern of immunoglobulin hypermutation in mice deficient in Slip-GC proteinThe Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination.Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.Refining the Neuberger model: Uracil processing by activated B cells.AID and somatic hypermutation.Hydroxymethylated cytosines are associated with elevated C to G transversion rates.Mismatch-mediated error prone repair at the immunoglobulin genes.Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligaseDoes DNA repair occur during somatic hypermutation?AIDing antibody diversity by error-prone mismatch repair.Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerasesPrimPol prevents APOBEC/AID family mediated DNA mutagenesisThe dual nature of mismatch repair as antimutator and mutator: for better or for worse.AID and APOBEC deaminases: balancing DNA damage in epigenetics and immunity.The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.
P2860
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P2860
Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Dependence of nucleotide subst ...... during somatic hypermutation.
@en
Dependence of nucleotide subst ...... during somatic hypermutation.
@nl
type
label
Dependence of nucleotide subst ...... during somatic hypermutation.
@en
Dependence of nucleotide subst ...... during somatic hypermutation.
@nl
prefLabel
Dependence of nucleotide subst ...... during somatic hypermutation.
@en
Dependence of nucleotide subst ...... during somatic hypermutation.
@nl
P2860
P356
P1476
Dependence of nucleotide subst ...... b during somatic hypermutation
@en
P2093
Paul C M van den Berk
Petra Langerak
P2860
P304
P356
10.1084/JEM.20091707
P407
P577
2009-11-09T00:00:00Z