Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7.
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Atg7 in development and disease: panacea or Pandora's Box?The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapyAutophagy and neurodegenerationMitochondria and the autophagy-inflammation-cell death axis in organismal agingAutophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Genetics and neuropathology of Huntington's diseaseMaintenance of basal levels of autophagy in Huntington's disease mouse models displaying metabolic dysfunctionSelective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivoAutophagy in neurodegenerative disorders: pathogenic roles and therapeutic implicationsGenetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients.Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease.The V471A polymorphism in autophagy-related gene ATG7 modifies age at onset specifically in Italian Huntington disease patients.Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?Exploring Genetic Factors Involved in Huntington Disease Age of Onset: E2F2 as a New Potential Modifier Gene.Autophagy-related gene 7 is downstream of heat shock protein 27 in the regulation of eye morphology, polyglutamine toxicity, and lifespan in DrosophilaProtein misfolding disorders and macroautophagy.Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins.Autophagy and neurodegenerative disorders.From pathways to targets: understanding the mechanisms behind polyglutamine disease.Iron and Neurodegeneration: Is Ferritinophagy the Link?Huntington's Disease: Relationship Between Phenotype and Genotype.Modern Genome Editing Technologies in Huntington's Disease Research.Autophagy in neurodegenerative diseases: pathogenesis and therapy.A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.Beneficial effects of rapamycin in a Drosophila model for hereditary spastic paraplegia.Genetic polymorphisms of ATG5 predict survival and recurrence in patients with early-stage esophageal squamous cell carcinoma.Aberrant regulation of autophagy in mammalian diseases.The p. R151C Polymorphism in MC1R Gene Modifies the Age of Onset in Spanish Huntington's Disease Patients.Inhibition of autophagy via p53-mediated disruption of ULK1 in a SCA7 polyglutamine disease model.
P2860
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P2860
Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@en
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@nl
type
label
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@en
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@nl
prefLabel
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@en
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@nl
P2093
P50
P1433
P1476
Age at onset in Huntington's d ...... he V471A polymorphism in Atg7.
@en
P2093
Hong Van Che
Liang Tong
Meiju Saukko
Yvonne Puder
P2888
P304
P356
10.1007/S00439-010-0873-9
P577
2010-08-10T00:00:00Z
P6179
1001270028