Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.
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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activityImmunoglobulin VH gene mutational analysis suggests that primary effusion lymphomas derive from different stages of B cell maturation.Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritisSomatic hypermutation of immunoglobulin and non-immunoglobulin genes.Neonatal immunity and somatic mutation.Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individualsHodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes.Assessment of antibody level and avidity against Bordetella pertussis in a cohort of Egyptian individuals aged 1-18 years.Hodgkin and Reed-Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells.Defect in IgV gene somatic hypermutation in common variable immuno-deficiency syndromeLoss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B-1 B cells.Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number.Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation.B-cell superantigens: molecular and cellular implications.Germinal center development.The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expressionBurkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes.Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells.Germinal center founder cells display propensity for apoptosis before onset of somatic mutation.Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing.Evidence of biased immunoglobulin variable gene usage in highly stable B-cell chronic lymphocytic leukemia.Somatic hypermutation of immunoglobulin genes is independent of the Bloom's syndrome DNA helicase.Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM.Memory B cell heterogeneity: Remembrance of things past.Somatic hypermutation in normal and transformed human B cells.AID expression during B-cell development: searching for answers.The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.Repertoire shift occurs during the memory maintenance phase of the immune responses and is not affinity-driven.Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue
P2860
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P2860
Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Variable region gene analysis ...... al blood already at young age.
@en
Variable region gene analysis ...... al blood already at young age.
@nl
type
label
Variable region gene analysis ...... al blood already at young age.
@en
Variable region gene analysis ...... al blood already at young age.
@nl
prefLabel
Variable region gene analysis ...... al blood already at young age.
@en
Variable region gene analysis ...... al blood already at young age.
@nl
P2860
P356
P1476
Variable region gene analysis ...... al blood already at young age.
@en
P2093
P2860
P304
P356
10.1084/JEM.180.4.1383
P407
P577
1994-10-01T00:00:00Z