Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.

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Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation.

P2860

Q54107721-531C0695-C82B-42E4-8DB7-42D3B18EF5F1

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Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.

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http://www.wikidata.org/entity/Q42951594

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

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2017年論文

@zh-hk

2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

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2017年论文

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name

Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

@en

Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

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type

Item

label

Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

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Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

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prefLabel

Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

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Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

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P1476

Inhibition of HIV-1 infection ...... rgeting small molecule 1E7-03.

@en

P2093

Amol Kulkarni

http://www.w3.org/2001/XMLSchema#string

Andrey Ivanov

http://www.w3.org/2001/XMLSchema#string

Aykut Üren

http://www.w3.org/2001/XMLSchema#string

Catherine DeMarino

http://www.w3.org/2001/XMLSchema#string

Fatah Kashanchi

http://www.w3.org/2001/XMLSchema#string

Kovalskyy Dmytro

http://www.w3.org/2001/XMLSchema#string

Marina Jerebtsova

http://www.w3.org/2001/XMLSchema#string

Namita Kumari

http://www.w3.org/2001/XMLSchema#string

Sergei Nekhai

http://www.w3.org/2001/XMLSchema#string

Tatiana Ammosova

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P2860

Nuclear protein phosphatase-1 regulates HIV-1 transcription

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription.

Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9

Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque

Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.

Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription

Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription

1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.

P304

76749-76769

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scholarly article

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10.18632/ONCOTARGET.19999

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P407

English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Guelaguetza Vazquez-Meves

P577

2017-08-07T00:00:00Z

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P698

29100346

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P932

5652740

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Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.

about

P2860

P2860

Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.

description

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P1433

P1476

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P1476

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