Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis.
about
Parkinson's disease, insulin resistance and novel agents of neuroprotectionCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringLinked clinical trials--the development of new clinical learning studies in Parkinson's disease using screening of multiple prospective new treatmentsExenatide and the treatment of patients with Parkinson's diseaseAnti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes.Exendin-4 improves blood glucose control in both young and aging normal non-diabetic mice, possible contribution of beta cell independent effects.Differential protective effects of exenatide, an agonist of GLP-1 receptor and Piragliatin, a glucokinase activator in beta cell response to streptozotocin-induced and endoplasmic reticulum stressesSaxagliptin restores vascular mitochondrial exercise response in the Goto-Kakizaki ratExendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.A noncytolytic antibody-like extendin-4-IgG4 fusion protein as a long-acting potential anti-diabetic agent.Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes.Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation.Microenvironmental stimuli for proliferation of functional islet β-cells.Novel incretin analogues improve autophagy and protect from mitochondrial stress induced by rotenone in SH-SY5Y cells.Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia.Exendin-4 reverts behavioural and neurochemical dysfunction in a pre-motor rodent model of Parkinson's disease with noradrenergic deficit.Tat-biliverdin reductase A protects INS-1 cells from human islet amyloid polypeptide-induced cytotoxicity by alleviating oxidative stress and ER stress.Recombination and functional studies of a dual-action peptide for diabetes.The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells.The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.Effects of chronic administration of alogliptin on the development of diabetes and β-cell function in high fat diet/streptozotocin diabetic mice.Current perspective of mitochondrial biology in Parkinson's disease.The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation.Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy
P2860
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P2860
Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@en
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@nl
type
label
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@en
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@nl
prefLabel
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@en
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@nl
P2093
P1476
Exendin-4 protects pancreatic ...... T and mitochondria biogenesis.
@en
P2093
P304
P356
10.1111/J.1463-1326.2010.01238.X
P50
P577
2010-09-01T00:00:00Z