Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.
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Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and diseaseStructural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide ReceptorCholine supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon actionHuman monoclonal antibodies against glucagon receptor improve glucose homeostasis by suppression of hepatic glucose output in diet-induced obese mice.Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathwayRemodeling of hepatic metabolism and hyperaminoacidemia in mice deficient in proglucagon-derived peptides.The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity.Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor.Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.Metabolic impact of glucagon deficiency.α-cell role in β-cell generation and regeneration.Islet α cells and glucagon--critical regulators of energy homeostasis.The New Biology and Pharmacology of Glucagon.Glucagon as a critical factor in the pathology of diabetesGlucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.Pretreatment of donor islets with the Na(+) /Ca(2+) exchanger inhibitor improves the efficiency of islet transplantation.Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists.
P2860
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P2860
Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@en
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@nl
type
label
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@en
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@nl
prefLabel
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@en
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@nl
P2093
P2860
P1476
Glucagon receptor antagonist-m ...... nal pancreatic GLP-1 receptor.
@en
P2093
Alykhan S Motani
Glenn Sivits
Ingrid C Rulifson
Katherine A Winters
Melissa Graham
Murielle M Véniant
Qingxiang Liu
Renée Komorowski
P2860
P304
P356
10.1152/AJPENDO.00102.2010
P577
2010-07-20T00:00:00Z