HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
about
Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsContributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells.Cooperative interactions at the SLP-76 complex are critical for actin polymerizationAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseBiophysical Aspects of T Lymphocyte Activation at the Immune SynapseComparative Anatomy of Phagocytic and Immunological SynapsesT Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific ImmunityT Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.The actin-bundling protein L-plastin supports T-cell motility and activationThe immunological synapse: the gateway to the HIV reservoirControversy and consensus regarding myosin II function at the immunological synapseMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseLigand mobility modulates immunological synapse formation and T cell activationRole of cortactin homolog HS1 in transendothelial migration of natural killer cellsActin nucleation at the centrosome controls lymphocyte polarity.Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapseTwo Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with VavDifferential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domainA point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunityThe lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells.The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactinSDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration.Immunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading.Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.The c-Abl tyrosine kinase regulates actin remodeling at the immune synapseCortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization.F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activationHematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreadingComputational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamicsStudies on the actin-binding protein HS1 in platelets.Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens.Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation.Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy.Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells.Using Murine Models to Investigate Tumor-Lymphoid Interactions: Spotlight on Chronic Lymphocytic Leukemia and Angioimmunoblastic T-Cell Lymphoma.HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen
P2860
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P2860
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@en
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@nl
type
label
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@en
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@nl
prefLabel
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@en
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@nl
P2093
P2860
P1433
P1476
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
@en
P2093
Bruce D Freedman
Christine M Labno
Daniel D Billadeau
David J Rawlings
Erin O Comiskey
Esteban Carrizosa
Janis K Burkhardt
Jeffrey C Nolz
Marcus R Clark
Peimin Zhu
P2860
P304
P356
10.1016/J.IMMUNI.2006.03.022
P407
P577
2006-06-01T00:00:00Z