Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
about
Towards a quantitative understanding of mitotic spindle assembly and mechanicsMolecular Insights into Division of Single Human Cancer Cells in On-Chip Transparent Microtubes.Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.P38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.The coupling between sister kinetochore directional instability and oscillations in centromere stretch in metaphase PtK1 cells.Mechanical impulses can control metaphase progression in a mammalian cellDeformations within moving kinetochores reveal different sites of active and passive force generation.Force on spindle microtubule minus ends moves chromosomesDirectly probing the mechanical properties of the spindle and its matrix.Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies.Using micromanipulation to analyze control of vertebrate meiotic spindle sizeAbnormal centrosome and spindle morphology in a patient with autosomal recessive primary microcephaly type 2 due to compound heterozygous WDR62 gene mutationMechanical control of mitotic progression in single animal cells.The role of actin and myosin in PtK2 spindle length changes induced by laser microbeam irradiations across the spindle.Insights into the micromechanical properties of the metaphase spindleLength-dependent anisotropic scaling of spindle shapeSpindle pole mechanics studied in mitotic asters: dynamic distribution of spindle forces through compliant linkages.Movement of chromosomes with severed kinetochore microtubules.Biophysics of mitosisCell shape impacts on the positioning of the mitotic spindle with respect to the substratum.Emergent Properties of the Metaphase Spindle.Fission yeast kinesin-8 controls chromosome congression independently of oscillationsWD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progressionAn allometric relationship between mitotic spindle width, spindle length, and ploidy in Caenorhabditis elegans embryos.Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.Patronin mediates a switch from kinesin-13-dependent poleward flux to anaphase B spindle elongationThe p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.Micromechanics of the vertebrate meiotic spindle examined by stretching along the pole-to-pole axis.Force and length in the mitotic spindle.Metaphase Spindle Assembly.Do nuclear envelope and intranuclear proteins reorganize during mitosis to form an elastic, hydrogel-like spindle matrix?Mitotic motors and chromosome segregation: the mechanism of anaphase B.How cells know the size of their organelles.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Intracellular Scaling Mechanisms.Size Scaling of Microtubule Assemblies in Early Xenopus Embryos.Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and Redundancy.Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation.Responses of chromosome segregation machinery to mechanical perturbations.Imaging and physically probing kinetochores in live dividing cells.
P2860
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P2860
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@en
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@nl
type
label
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@en
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@nl
prefLabel
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@en
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@nl
P2860
P1433
P1476
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
@en
P2093
Sophie Dumont
Timothy J Mitchison
P2860
P304
P356
10.1016/J.CUB.2009.05.056
P407
P577
2009-06-18T00:00:00Z