Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. - Wikidata - wikimedia - TriplyDB

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

http://www.wikidata.org/entity/Q43077169

about

Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13 New insights into repeat instability: role of RNA•DNA hybrids The balancing act of DNA repeat expansions The hidden side of unstable DNA repeats: Mutagenesis at a distance GFP-based fluorescence assay for CAG repeat instability in cultured human cells Timeless preserves telomere length by promoting efficient DNA replication through human telomeres Progressive GAA.TTC repeat expansion in human cell lines.Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.Srs2: the "Odd-Job Man" in DNA repair.Friedreich's ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae.Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation.Triplex technology in studies of DNA damage, DNA repair, and mutagenesis NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at postreplication gaps.Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability Timeless protection of telomeres.Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complex Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast.Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae.Tandem repeats and G-rich sequences are enriched at human CNV breakpoints Mechanisms of trinucleotide repeat instability during human development Repeat instability during DNA repair: Insights from model systems Is Friedreich ataxia an epigenetic disorder?Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis Azidothymidine and other chain terminators are mutagenic for template-switch-generated genetic mutations.Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instability Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.Mature microsatellites: mechanisms underlying dinucleotide microsatellite mutational biases in human cells.Mutation at a distance caused by homopolymeric guanine repeats in Saccharomyces cerevisiae Inhibition of DNA synthesis facilitates expansion of low-complexity repeats: is strand slippage stimulated by transient local depletion of specific dNTPs?Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.Genome rearrangements caused by interstitial telomeric sequences in yeast.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Current and emerging treatment options in the management of Friedreich ataxia.Ubiquitin family modifications and template switching.Local and global functions of Timeless and Tipin in replication fork protection.The yin and yang of repair mechanisms in DNA structure-induced genetic instability.Impediments to replication fork movement: stabilisation, reactivation and genome instability.Gene regulation and epigenetics in Friedreich's ataxia.

P2860

Q21144902-35C0D4BE-E8D2-414D-BC0F-60AFA090F1E0 Q24621985-5E39B5C8-F286-4ADC-8C97-9BBF3287ACC0 Q27001959-10A43F35-18DC-4B04-8865-5C373C0F57AA Q27027501-D1FEC4DA-F030-4E20-8407-B98BDD4EDCB0 Q28545187-C515088C-3255-4624-9379-9CF52E88DF4D Q29041627-0851ED55-2FD9-4962-9D40-30CD7E9210DC Q33513958-BB2858C1-83D8-4AFC-9DB8-0DE5FB6CCBCF Q33636060-935223C3-4787-499C-84F4-CBA2CFB32995 Q33754225-76D1C47A-2861-4BAB-8117-C1522B93FDDB Q33797851-2F73C6A9-3878-43B9-BC1E-D2E516C64333 Q33851243-6F67392E-7C68-4B2F-B28C-7964A86A2236 Q34117236-E3526E7F-7578-4463-865F-1FCE3B1781F6 Q34179182-2E2EA145-2090-45DD-A929-CC5138B3CDCA Q34216700-1F76C453-4C79-49C8-AAD1-8CBB22BC8211 Q34330367-8161171C-D583-4AEF-8E05-1805DBE3E6B5 Q34521770-69CA9BA0-486F-4C3A-8623-A7952FC00B67 Q34561912-BC9C5A35-F5F8-4438-913E-29890C6ED9E1 Q34582933-4B65B40E-892A-4D6F-802C-71DD672D12B4 Q34778532-5D2B1D82-63D5-458D-839C-CD5B7D66559D Q35199018-D02A6C9A-562C-4A2B-A392-E9FDE4FD56C1 Q35219284-1768CFAC-F553-4236-B21F-92BDA9A0C649 Q35680075-8625FE15-F717-4BF1-8AE4-8568136504C0 Q35833870-0CACF473-2E94-4C3F-A38D-24B0778829ED Q35847997-BFB6279A-C5EA-49A9-ABF5-A8A79D8FBCAD Q35924896-3C4F2B9C-78B4-4081-A32A-E25151A6C39E Q35943348-813950D6-6A26-46CF-8429-CFD2B4C728E0 Q36051360-C525D56D-D489-426B-845B-1E69A974EB8E Q36216018-EC206803-5A65-4F27-815F-C5A0FC45AF36 Q36642236-32B46A32-176B-4582-B45F-61B4D432414F Q37056244-81D559C8-8481-4C06-9F3D-A4B613E7758F Q37149212-A9A4E132-5E69-467A-B2EF-EE6A95AE7AB7 Q37266016-E05FD0AE-DEB0-4248-BA20-0C5A546AAE1B Q37377363-51096053-E0C3-4302-B315-7EDECA2DFCD6 Q37483304-E45162D6-4865-4BFD-A8BC-E9F5EC9403A4 Q37790615-65FC06D0-EC3A-4A9A-9CCF-B823D0D6AB20 Q37871655-8FFAE88A-8F77-4323-8E9C-63D6F36DF724 Q38044291-BFD555C4-B0DA-428D-BAD2-E572DDB9C13C Q38065578-360E7EDE-FC4B-47CF-91DF-9BC7917D26FF Q38085184-B59E2CA0-21A6-4717-960D-9AA4226208C9 Q38121941-7AA8BEE1-B1D5-487D-B211-458D33A89801

P2860

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

http://www.wikidata.org/entity/Q43077169

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@en

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@nl

type

label

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@en

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@nl

prefLabel

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@en

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@nl

P1433

Q43077169-2FC17135-5A5A-4CAE-AB00-37A0493F970D

P1476

Q43077169-93045021-0B14-4CE1-B8CC-319DBE12F4B3

P2093

Q43077169-053B5DD5-2F64-4E09-AA2C-59A69576D230

Q43077169-10D7508A-7F79-4426-8B37-1E8085D5B3EA

Q43077169-256EC3F6-EA70-4950-A687-51AF3A0B9AE4

Q43077169-3FC3431E-CD8E-4939-BA31-9A98DB2086AB

Q43077169-4C44B021-B2FC-4AF3-A65F-58F4144C44A4

Q43077169-5A09670E-1E7F-4203-9496-05BFA13053F6

Q43077169-735434DD-4A53-4A49-8D7B-D0A6C29D0CE6

Q43077169-7605AFFE-6181-4B30-9847-CC8BDFA77E9C

Q43077169-EFE69F26-F679-4917-9B5E-8CBC6D38322F

P2860

Q43077169-002DD493-86F9-40F3-B34A-4C5D57553B82

Q43077169-03923060-96CA-467E-923C-D904BA44DE97

Q43077169-05C2CCF6-794B-4909-A61C-8E784D93F4CF

Q43077169-06302ACD-4063-4488-A5BF-CF63A3697627

Q43077169-079CCBB4-C5E9-4C56-9E2E-EA6C0E8B24C3

Q43077169-0C73B67E-3AF9-4758-BA85-24610F0C35CF

Q43077169-13D02FF8-CAB7-441F-8E5D-BBEA9C3304D5

Q43077169-159FE938-5D60-4D23-B3CF-90BB7DDB327C

Q43077169-1C1B1E31-51C5-4EF9-A3D0-63BD3A56E432

Q43077169-1C8D66FC-1AE4-44CD-B839-FF1485E4CEC6

P304

Q43077169-7EB0DF3C-641B-4165-B7ED-3237B4E2A537

P31

Q43077169-9D74E7A3-1C4A-4B9D-B721-FAC679A97A14

P356

Q43077169-65D667BE-00B7-4604-9D5E-8F6E6C1CE386

P433

Q43077169-708D1E6A-3C1E-453B-8946-093DD1174977

P478

Q43077169-6FD19796-34ED-4862-967A-DCD5CB1A421D

P577

Q43077169-8E043BE6-A162-4C1C-845A-7C60CAD03127

P5875

Q43077169-0A2320D4-CC41-4469-A6FB-66AC8CFA2038

P698

Q43077169-2D9197F5-5FEB-4BDC-95DA-3D46FCCC7283

P932

Q43077169-623EE6D2-21E3-46BD-8836-E309E02BAD7B

P356

J.MOLCEL.2009.06.017

P1433

P1476

Large-scale expansions of Friedreich's ataxia GAA repeats in yeast.

@en

P2093

Alexander A Shishkin

http://www.w3.org/2001/XMLSchema#string

Brook T Chernet

http://www.w3.org/2001/XMLSchema#string

Irina Voineagu

http://www.w3.org/2001/XMLSchema#string

Kirill S Lobachev

http://www.w3.org/2001/XMLSchema#string

Maria M Krasilnikova

http://www.w3.org/2001/XMLSchema#string

Nicole Cherng

http://www.w3.org/2001/XMLSchema#string

Robert Matera

http://www.w3.org/2001/XMLSchema#string

Sergei M Mirkin

http://www.w3.org/2001/XMLSchema#string

Vidhya Narayanan

http://www.w3.org/2001/XMLSchema#string

P2860

The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure

Influence of Friedreich ataxia GAA noncoding repeat expansions on pre-mRNA processing

Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins

Advances in mechanisms of genetic instability related to hereditary neurological diseases.

Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression.

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex.

Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex.

The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae

P304

82-92

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MOLCEL.2009.06.017

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

35

http://www.w3.org/2001/XMLSchema#string

P577

2009-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26664456

http://www.w3.org/2001/XMLSchema#string

P698

19595718

http://www.w3.org/2001/XMLSchema#string

P932

2722067

http://www.w3.org/2001/XMLSchema#string