p53 as a target in myeloproliferative neoplasms.

about

The orally bioavailable MDM2 antagonist RG7112 and pegylated interferon α 2a target JAK2V617F-positive progenitor and stem cells.A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells.

P2860

Q35743852-300B60CA-9C10-4E21-AC6F-CB232706FBB9 Q51735874-BDC5585A-5307-4910-A253-66F381B88AE9

P2860

p53 as a target in myeloproliferative neoplasms.

Item

http://www.wikidata.org/entity/Q43082960

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh-hant

name

p53 as a target in myeloproliferative neoplasms.

@en

p53 as a target in myeloproliferative neoplasms.

@nl

type

Item

label

p53 as a target in myeloproliferative neoplasms.

@en

p53 as a target in myeloproliferative neoplasms.

@nl

prefLabel

p53 as a target in myeloproliferative neoplasms.

@en

p53 as a target in myeloproliferative neoplasms.

@nl

P1476

p53 as a target in myeloproliferative neoplasms.

@en

P2093

Min Lu

http://www.w3.org/2001/XMLSchema#string

Ronald Hoffman

http://www.w3.org/2001/XMLSchema#string

P2860

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis.

Interferon-alpha targets JAK2V617F-positive hematopoietic progenitor cells and acts through the p38 MAPK pathway.

Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cells

MDM2 inhibitors for cancer therapy.

The renaissance of interferon therapy for the treatment of myeloid malignancies.

JAK2(V617F) negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms.

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis.

P304

1052-1053

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

editorial

P356

10.18632/ONCOTARGET.719

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2012-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

233724574

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P698

23165648

http://www.w3.org/2001/XMLSchema#string

P932

3717951

http://www.w3.org/2001/XMLSchema#string

p53 as a target in myeloproliferative neoplasms.

about

P2860

P2860

p53 as a target in myeloproliferative neoplasms.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932