The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time.
about
At short telomeres Tel1 directs early replication and phosphorylates Rif1.A role for the nucleoporin Nup170p in chromatin structure and gene silencing.The ELG1 clamp loader plays a role in sister chromatid cohesionEarly initiation of a replication origin tethered at the nuclear peripheryQuantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint.The budding yeast nucleus.Functional centromeres determine the activation time of pericentric origins of DNA replication in Saccharomyces cerevisiae.DNA replication timingThe effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation.The Ctf18RFC clamp loader is essential for telomere stability in telomerase-negative and mre11 mutant alleles.The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication.TFIIIC localizes budding yeast ETC sites to the nuclear periphery.Mdt1 facilitates efficient repair of blocked DNA double-strand breaks and recombinational maintenance of telomeres.Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast.Differential nuclear localization does not determine the silencing status of Saccharomyces cerevisiae telomeres.Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombinationIs PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?Spatial regulation and organization of DNA replication within the nucleus.Molecular analysis of the replication program in unicellular model organisms.Location, location, location: it's all in the timing for replication origins.Protein phosphatase 1 recruitment by Rif1 regulates DNA replication origin firing by counteracting DDK activity.Structural studies of RFCCtf18 reveal a novel chromatin recruitment role for Dcc1.Control of Genome Integrity by RFC Complexes; Conductors of PCNA Loading onto and Unloading from Chromatin during DNA Replication.The yeast telomerase RNA, TLC1, participates in two distinct modes of TLC1-TLC1 association processes in vivo.Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp.Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast.Release of yeast telomeres from the nuclear periphery is triggered by replication and maintained by suppression of Ku-mediated anchoring.A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1.Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning.Alternative clamp loaders/unloaders.Distinct 'safe zones' at the nuclear envelope ensure robust replication of heterochromatic chromosome regions.
P2860
Q27929847-21449CE6-2D2B-4B3C-ADCD-F9F100AA67BFQ27938031-0C3429C1-EA9B-4882-8077-1C1BF116BFEBQ27938884-AC9C4F7C-71BF-49DD-9E7F-4FBD8F73C98CQ33748588-878B2BD1-AF09-4219-8C9C-5C5B61AF4869Q33877191-E14C674D-9F9F-4409-AEC9-6B167282176BQ34014665-6CF7FCEF-96D0-46BC-9B82-C08925405CF2Q34270486-E6800483-73CB-4211-836D-AA738FF64E87Q34654036-C3FBF751-90D5-4D8F-B364-4AD6757FBE52Q34977327-CA0F5DF7-C70A-4554-8E84-DAABBE77B914Q35095480-8FCB1CE3-DEDE-4A35-9091-13CC4D8FE34AQ35844875-2F861A67-E818-48F7-A683-D0DD73E6F2EAQ36091842-40507C70-90EF-424E-B450-89EFFEF00EA6Q36177491-0B7571A0-078E-4C19-AB88-69F0D119D611Q36388826-4B913713-FCE2-4A1F-91FB-47BEB0397875Q36416213-45F73290-E11B-448D-B572-FCEC60C8B1B3Q37175957-EDD47B0F-8B44-47A0-AC4A-5C3FF34C6D9DQ37396901-4D56AB65-3A91-407E-902B-98AA35570A74Q37621327-43CB53DC-1227-4BD1-AE86-7163FB286D1EQ37685965-CDDFE109-3439-4155-9C4C-A276EEED5906Q38076662-165BF859-3DD7-4CF7-B6F9-3341DBD5464EQ38799800-26459B71-10B4-46A1-B7C2-A10B56069AA8Q38966656-359B8088-2D34-4EF6-B631-5C8C18067727Q39109267-29EECF2E-14FF-4163-ABED-EC7D6D447FEBQ39241123-AF89258A-F910-41D4-8395-5CBBE29FC1AEQ40335075-26029F03-CA7A-41C0-B772-3B916EB66E48Q40975957-0E1D032B-28C1-421A-811D-D2345E970D05Q41788797-ABFCB836-6B81-4DA6-8294-58CF25BA4939Q41861289-07864CD7-E4A8-4844-AB27-1D72742101D1Q43243209-45CA81CC-8783-4454-B188-93A1BA14F762Q51466334-98CA594C-AEBD-40C4-8B8D-FE5DD08D3DCBQ54967259-17F9C3D6-EFB9-4192-815D-2D01B715BC11
P2860
The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@en
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@nl
type
label
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@en
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@nl
prefLabel
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@en
The Ctf18 RFC-like complex pos ...... pecify their replication time.
@nl
P2860
P356
P1433
P1476
The Ctf18 RFC-like complex pos ...... specify their replication time
@en
P2093
E Douglas Robertson
P2860
P304
P356
10.1038/SJ.EMBOJ.7601038
P407
P577
2006-03-09T00:00:00Z