about
Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRbDetermination of the consensus binding sequence for the purified embryonic heat shock factor 2.Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidanceBrain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice.The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels.Role of Pax6 in forebrain regionalization.Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealizationCyclosporin A induces an atypical heat shock response.The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice.Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer.Heat-shock genes and development.Genomic structure and chromosomal localization of the mouse Hsf2 gene and promoter sequences.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Martine Manuel
@ast
Martine Manuel
@en
Martine Manuel
@es
Martine Manuel
@nl
Martine Manuel
@sl
type
label
Martine Manuel
@ast
Martine Manuel
@en
Martine Manuel
@es
Martine Manuel
@nl
Martine Manuel
@sl
prefLabel
Martine Manuel
@ast
Martine Manuel
@en
Martine Manuel
@es
Martine Manuel
@nl
Martine Manuel
@sl
P106
P21
P31
P496
0000-0001-7674-8785