Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization
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Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergenceSustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse NeocortexDifferential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome systemPax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRbThe level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesisThe doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammalsGdf11 facilitates temporal progression of neurogenesis in the developing spinal cordEr81 is a downstream target of Pax6 in cortical progenitors.Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidanceA Boolean model of the gene regulatory network underlying Mammalian cortical area developmentDNaseI hypersensitivity and ultraconservation reveal novel, interdependent long-range enhancers at the complex Pax6 cis-regulatory region.Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasisABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice.The cortical hem regulates the size and patterning of neocortexThe generation of superficial cortical layers is regulated by levels of the transcription factor Pax6Pax6 is essential for the maintenance and multi-lineage differentiation of neural stem cells, and for neuronal incorporation into the adult olfactory bulb.Gradients in the brain: the control of the development of form and function in the cerebral cortex.The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels.Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines.Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation.Lessons from mouse chimaera experiments with a reiterated transgene marker: revised marker criteria and a review of chimaera markersRegional Volume Decreases in the Brain of Pax6 Heterozygous Mutant Rats: MRI Deformation-Based MorphometryAnnual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disordersLateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitorsTranscriptional and epigenetic mechanisms of early cortical development: An examination of how Pax6 coordinates cortical development.Relationship of Pax6 activity levels to the extent of eye development in the mouse, Mus musculusA microRNA-328 binding site in PAX6 is associated with centrotemporal spikes of rolandic epilepsy.Activation of Pax3 target genes is necessary but not sufficient for neurogenesis in the ophthalmic trigeminal placode.Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development.Genetic regulation of arealization of the neocortexAltered molecular regionalization and normal thalamocortical connections in cortex-specific Pax6 knock-out mice.Effects of elevated Pax6 expression and genetic background on mouse eye development.The role of Pax6 in forebrain development.Neocortical arealization: evolution, mechanisms, and open questions.Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor.The long non-coding RNA Paupar regulates the expression of both local and distal genes.Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish.Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6.
P2860
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P2860
Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Controlled overexpression of P ...... ffect on cortical arealization
@ast
Controlled overexpression of P ...... ffect on cortical arealization
@en
type
label
Controlled overexpression of P ...... ffect on cortical arealization
@ast
Controlled overexpression of P ...... ffect on cortical arealization
@en
prefLabel
Controlled overexpression of P ...... ffect on cortical arealization
@ast
Controlled overexpression of P ...... ffect on cortical arealization
@en
P2093
P2860
P50
P356
P1433
P1476
Controlled overexpression of P ...... ffect on cortical arealization
@en
P2093
Ben Martynoga
Catherine B Carr
David A Tyas
Jeni Pinson
John D West
Michael Molinek
Petrina A Georgala
Simon Chanas
T Ian Simpson
P2860
P304
P356
10.1242/DEV.02764
P407
P50
P577
2007-01-03T00:00:00Z