Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice.
about
Regulation of Bim in Health and DiseaseMitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunityTransforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.Bim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death.Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiencyBH3-only molecule Bim mediates β-cell death in IRS2 deficiency.Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation.Bcl-2-regulated cell death signalling in the prevention of autoimmunity.Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice.Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunityProapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.Bim is required for T-cell allogeneic responses and graft-versus-host disease in vivo.Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in miceSelective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T LymphocytesT cell Bim levels reflect responses to anti-PD-1 cancer therapy.Apoptosis and autophagy: decoding calcium signals that mediate life or death.Shaping the T-cell repertoire: a matter of life and death.Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: role in Ca(2+) signaling and disease.Non-apoptotic functions of BCL-2 family proteins.IER3IP1 deficiency leads to increased β-cell death and decreased β-cell proliferation.Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells.Leukocyte Bim deficiency does not impact atherogenesis in ldlr -/- mice, despite a pronounced induction of autoimmune inflammation.p27(Kip1) inhibits systemic autoimmunity through the control of Treg cell activity and differentiation.Exacerbation of spontaneous autoimmune nephritis following regulatory T cell depletion in B cell lymphoma 2-interacting mediator knock-out mice.
P2860
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P2860
Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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name
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@en
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@nl
type
label
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@en
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@nl
prefLabel
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@en
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@nl
P2093
P2860
P356
P1476
Critical roles of Bim in T cel ...... oimmune inflammation in mice.
@en
P2093
Brendan Hilliard
Jennifer DeVirgiliis
Maciej W Ludwinski
Ruaidhri J Carmody
Youhai H Chen
P2860
P304
P356
10.1172/JCI37619
P407
P50
P577
2009-06-01T00:00:00Z