Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
about
Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophyABCD2 alters peroxisome proliferator-activated receptor α signaling in vitro, but does not impair responses to fenofibrate therapy in a mouse model of diet-induced obesityPathomechanisms underlying X-adrenoleukodystrophy: a three-hit hypothesis.Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy.Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells.Autophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy.Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes.ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy.Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophyInduction of mitochondrial changes associated with oxidative stress on very long chain fatty acids (C22:0, C24:0, or C26:0)-treated human neuronal cells (SK-NB-E).Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.Glutathione imbalance in patients with X-linked adrenoleukodystrophyTauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy.Myelin lesions associated with lysosomal and peroxisomal disorders.Oxidative Stress in Patients with X-Linked Adrenoleukodystrophy.A Thyroid Hormone-Based Strategy for Correcting the Biochemical Abnormality in X-Linked Adrenoleukodystrophy.X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism is severely impaired in monocytes but not in lymphocytes.Evidence of Oxidative Stress and Secondary Mitochondrial Dysfunction in Metabolic and Non-Metabolic Disorders.The effects of vitamin B6 on lens antioxidant system in valproic acid-administered rats.Metformin-induced mitochondrial function and ABCD2 up-regulation in X-linked adrenoleukodystrophy involves AMP-activated protein kinase.Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy.Vitamin U, a novel free radical scavenger, prevents lens injury in rats administered with valproic acid.Effect of Lorenzo's Oil on Hepatic Gene Expression and the Serum Fatty Acid Level in abcd1-Deficient Mice.
P2860
Q24618949-C746124F-AAD7-4918-8CB5-BF468FD958D3Q34360091-BA4B642F-CEBB-4F52-A455-F1799886F556Q34491978-23F75568-1EC7-46B0-A620-C44E5A1AC48DQ34631169-01D23B23-1755-449F-A240-57FB62E8B63BQ34907267-46D06529-9F8D-40E1-8455-6E49E44B55C7Q35092638-902B4775-3542-4E48-AFC7-5016B08ABE0FQ35193956-1210D4F0-76C8-446A-8240-5AF40B765AFAQ35380239-8A655A73-D880-4845-B8A6-2CA872A3B2CBQ35417932-CD2D47CA-7595-4B44-90FD-39EB853FE391Q35997389-608E470E-7CCD-4511-8967-1E2C45DBD66EQ36167749-B3C01A1C-D2E8-4E8A-9370-D5ACA124593DQ36288305-EA1A038A-4D7C-420F-BC7C-BC9DF2266D0AQ36713344-857D5B27-9AF3-40F5-9DD5-A32FD34ACD57Q37066947-2A8BCFDB-5433-4729-B4CE-7E24AB96C1DAQ37596791-D89F965C-4245-4DEF-B863-5A436F6D3848Q37785556-C09471A3-04D1-40B8-8FCD-845E52B46862Q38546277-AE85718C-460C-4DC8-996A-8D073F815EF6Q38716382-CE0EFBA5-E6B7-4A0A-B913-FE356712D106Q38806290-FB80431F-9063-4747-9301-ACA34342D99AQ41161393-6995E2FE-AF9C-4A5C-9E96-2C6D906E5EDFQ47963313-829D402C-4F90-4AC9-A1BE-0194BFBDA883Q48925414-8C7C05A1-E385-4AA8-85BF-DB14AD8FD661Q51055442-5276A6E6-AC96-4FA6-9ABE-FDB1B627EAC0Q51069192-81317A73-4396-4509-B1D4-5DF4626E6008Q54944139-6D44C1E6-1375-4F6C-B913-5EE1F31E30AE
P2860
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@en
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@nl
type
label
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@en
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@nl
prefLabel
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@en
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@nl
P2093
P2860
P50
P356
P1476
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
@en
P2093
Brunhilde Wirth
Eric Hahnen
Georges Dacremont
Lars Brichta
Manuel Portero-Otín
Nathalie Cartier
Patrick Aubourg
P2860
P304
P356
10.1093/HMG/DDQ082
P50
P577
2010-02-23T00:00:00Z