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Clustering by plasma lipoprotein profile reveals two distinct subgroups with positive lipid response to fenofibrate therapyNutritional systems biology modeling: from molecular mechanisms to physiology.Beyond diversity: functional microbiomics of the human colon.Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation.Pathway analysis and metabolic engineering in Corynebacterium glutamicum.Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria.Lipoprotein metabolism indicators improve cardiovascular risk prediction.Gaining insight into microbial physiology in the large intestine: a special role for stable isotopes.The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: a systems biology approach.A systematic approach to obtain validated partial least square models for predicting lipoprotein subclasses from serum NMR spectra.Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.The onset of type 2 diabetes: proposal for a multi-scale model.A new flexible plug and play scheme for modeling, simulating, and predicting gastric emptyingMetabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy.Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo.Response of the central metabolism of Corynebacterium glutamicum to different flux burdens.Changes of pentose phosphate pathway flux in vivo in Corynebacterium glutamicum during leucine-limited batch cultivation as determined from intracellular metabolite concentration measurements.Metabolic phenotype of phosphoglucose isomerase mutants of Corynebacterium glutamicum.Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni.Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA-based stable isotope probing.Profiling human gut bacterial metabolism and its kinetics using [U-13C]glucose and NMR.Identification of glucose-fermenting bacteria present in an in vitro model of the human intestine by RNA-stable isotope probing.Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations.The effect of plant sterols and different low doses of omega-3 fatty acids from fish oil on lipoprotein subclasses.Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis.Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments.Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems.13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approachesBidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments.Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.C3-carboxylation as an anaplerotic reaction in phosphoenolpyruvate carboxylase-deficient Corynebacterium glutamicumAccurate determination of 13C enrichments in nonprotonated carbon atoms of isotopically enriched amino acids by 1H nuclear magnetic resonanceDetermination of full 13C isotopomer distributions for metabolic flux analysis using heteronuclear spin echo difference NMR spectroscopyKinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose phosphate pathway flux in vivoResponse of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenaseA universal framework for 13C metabolic flux analysisA metabolic flux analysis to study the role of sucrose synthase in the regulation of the carbon partitioning in central metabolism in maize root tipsA physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Albert de Graaf
@ast
Albert de Graaf
@en
Albert de Graaf
@es
Albert de Graaf
@nl
type
label
Albert de Graaf
@ast
Albert de Graaf
@en
Albert de Graaf
@es
Albert de Graaf
@nl
prefLabel
Albert de Graaf
@ast
Albert de Graaf
@en
Albert de Graaf
@es
Albert de Graaf
@nl
P106
P21
P31
P496
0000-0002-1067-3570