Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.
about
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunityRegulatory T-Cell Development in the Human ThymusCellular and molecular determinants for the development of natural and induced regulatory T cellsNature and nurture in Foxp3(+) regulatory T cell development, stability, and functionH2 control of natural T regulatory cell frequency in the lymph node correlates with susceptibility to day 3 thymectomy-induced autoimmune diseaseRapid and selective expansion of nonclonotypic T cells in regulatory T cell-deficient, foreign antigen-specific TCR-transgenic scurfy mice: antigen-dependent expansion and TCR analysis.Rare development of Foxp3+ thymocytes in the CD4+CD8+ subsetDevelopment of thymically derived natural regulatory T cells.Hematopoietic chimerism and transplantation tolerance: a role for regulatory T cells.Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction.Differentiation of regulatory Foxp3+ T cells in the thymic cortex.Fetal exposure to high-avidity TCR ligand enhances expansion of peripheral T regulatory cells.Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.The T-cell receptor repertoire of regulatory T cells.Learning to be tolerant: how T cells keep out of trouble.Finding their niche: chemokines directing cell migration in the thymus.IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes.Adaptive immunity: Based on the dual recognition responses of αβT cells.Foxp3 induction in human and murine thymus precedes the CD4+ CD8+ stage but requires early T-cell receptor expression.High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
P2860
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P2860
Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Shaping of the autoreactive re ...... c cortical positive selection.
@en
Shaping of the autoreactive re ...... c cortical positive selection.
@nl
type
label
Shaping of the autoreactive re ...... c cortical positive selection.
@en
Shaping of the autoreactive re ...... c cortical positive selection.
@nl
prefLabel
Shaping of the autoreactive re ...... c cortical positive selection.
@en
Shaping of the autoreactive re ...... c cortical positive selection.
@nl
P2093
P2860
P1476
Shaping of the autoreactive re ...... c cortical positive selection.
@en
P2093
Anne Huchenq
Denis Hudrisier
Geneviève Enault
Joost P M van Meerwijk
Julie Ribot
Maryline Calise
Paola Romagnoli
Sylvie Pilipenko
P2860
P304
P356
10.4049/JIMMUNOL.179.10.6741
P407
P577
2007-11-01T00:00:00Z