Fibrin clot retraction by human platelets correlates with alpha(IIb)beta(3) integrin-dependent protein tyrosine dephosphorylation.
about
The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingRGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signallingImmunoglobulin M antiplatelet autoantibodies from mice immunized with rat platelets induce thrombocytopenia and platelet function impairment.Soluble TLT-1 modulates platelet-endothelial cell interactions and actin polymerization.Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.Elastic behavior and platelet retraction in low- and high-density fibrin gels.The interaction of integrin αIIbβ3 with fibrin occurs through multiple binding sites in the αIIb β-propeller domain.MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activationA critical role for the transient receptor potential channel type 6 in human platelet activationSynthetic Strategies for Engineering Intravenous Hemostats.Platelet integrins and immunoreceptors.Application of microfluidic devices in studies of thrombosis and hemostasis.Reduced clot retraction rate and altered platelet energy production in patients with asthma.Involvement of Src kinases and PLCgamma2 in clot retraction.Silver nano particles prevent platelet adhesion on immobilized fibrinogenThe incidence and magnitude of fibrinolytic activation in trauma patients: a rebuttal.Role of G protein signaling in the formation of the fibrin(ogen)-integrin αIIbβ3-actin cytoskeleton complex in platelets.Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen.Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen-integrin αIIb β3 binding in human platelets.Clinically relevant HOCl concentrations reduce clot retraction rate via the inhibition of energy production in platelet mitochondria.The contributions of integrin affinity and integrin-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin.
P2860
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P2860
Fibrin clot retraction by human platelets correlates with alpha(IIb)beta(3) integrin-dependent protein tyrosine dephosphorylation.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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name
Fibrin clot retraction by human platelets correlates with alpha
@nl
Fibrin clot retraction by huma ...... in tyrosine dephosphorylation.
@en
type
label
Fibrin clot retraction by human platelets correlates with alpha
@nl
Fibrin clot retraction by huma ...... in tyrosine dephosphorylation.
@en
prefLabel
Fibrin clot retraction by human platelets correlates with alpha
@nl
Fibrin clot retraction by huma ...... in tyrosine dephosphorylation.
@en
P2860
P356
P1476
Fibrin clot retraction by huma ...... in tyrosine dephosphorylation.
@en
P2093
P2860
P304
P356
10.1074/JBC.M008945200
P407
P577
2000-11-17T00:00:00Z