Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter.
about
ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-IThe ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier diseaseThe interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipidsCerebrospinal Fluid Particles in Alzheimer Disease and Parkinson DiseaseMolecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain proteinRegulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion developmentHepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDLPhosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter.Transbilayer phospholipid movements in ABCA1-deficient cells.Model system for the analysis of cell surface expression of human ABCA1.ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.Control of cholesterol turnover in the mouse.The role of human T-lymphocyte-monocyte contact in inflammation and tissue destructionRegulation and mechanisms of macrophage cholesterol effluxABCA1: regulation, trafficking and association with heteromeric proteins.High density lipoprotein structure-function and role in reverse cholesterol transport.ABCA1 and atherosclerosis.Discrete roles of apoA-I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models.Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.Lipid outward translocation by ABC proteins.Function and regulation of ABCA1--membrane meso-domain organization and reorganization.Contribution of monocyte-derived macrophages and smooth muscle cells to arterial foam cell formation.ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis.ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.Increased ABCA1 activity protects against atherosclerosis.ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I bindingPotential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL.ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.Liver-X-receptor-mediated increase in ATP-binding cassette transporter A1 expression is attenuated by fatty acids in CaCo-2 cells: effect on cholesterol efflux to high-density lipoprotein.Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells.Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly.Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes.Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux.Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation.PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly.Brefeldin A inhibits cholesterol efflux without affecting the rate of cellular uptake and re-secretion of apolipoprotein A-I in adipocytes.ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein.Polarized cholesterol and phospholipid efflux in cultured gall-bladder epithelial cells: evidence for an ABCA1-mediated pathway.
P2860
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P2860
Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Specific docking of apolipopro ...... functional ABCA1 transporter.
@en
Specific docking of apolipopro ...... functional ABCA1 transporter.
@nl
type
label
Specific docking of apolipopro ...... functional ABCA1 transporter.
@en
Specific docking of apolipopro ...... functional ABCA1 transporter.
@nl
prefLabel
Specific docking of apolipopro ...... functional ABCA1 transporter.
@en
Specific docking of apolipopro ...... functional ABCA1 transporter.
@nl
P2093
P356
P1476
Specific docking of apolipopro ...... functional ABCA1 transporter.
@en
P2093
P304
P356
10.1074/JBC.M010265200
P407
P577
2001-01-09T00:00:00Z