ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease.
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Retina, retinol, retinal and the natural history of vitamin A as a light sensorThe lipid translocase, ABCA4: seeing is believing.Photoreceptor renewal: a role for peripherin/rdsIsomerization of 11-cis-retinoids to all-trans-retinoids in vitro and in vivo.The interphotoreceptor retinoid-binding protein (IRBP) of the chicken (Gallus gallus domesticus)Evidence that light modulates protein nitration in rat retina.PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis.Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cellsQuantitative measurements of autofluorescence with the scanning laser ophthalmoscopeA model of spectral filtering to reduce photochemical damage in age-related macular degeneration.Interpretations of fundus autofluorescence from studies of the bisretinoids of the retinaMicrosomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging.A2E and blue light in the retina: the paradigm of age-related macular degeneration.Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium.Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment.Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4The bisretinoids of retinal pigment epitheliumRetinal photodamage mediated by all-trans-retinal.Energy metabolism of the visual system.Primary amines protect against retinal degeneration in mouse models of retinopathies.Diseases of intramembranous lipid transport.Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage.ABCA4 gene analysis in patients with autosomal recessive cone and cone rod dystrophies.Retinal photodamage by endogenous and xenobiotic agents.Photo-damage, photo-protection and age-related macular degeneration.The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems.Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration.Mutations in ABCA4 result in accumulation of lipofuscin before slowing of the retinoid cycle: a reappraisal of the human disease sequence.Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma.Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma.Neurodegenerative diseases of the retina and potential for protection and recoveryAll-trans retinal mediates light-induced oxidation in single living rod photoreceptors.Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin.Retinal Histopathology in Eyes from a Patient with Stargardt disease caused by Compound Heterozygous ABCA4 Mutations.Removal of the blue component of light significantly decreases retinal damage after high intensity exposure.Functionally Active Membrane Proteins Incorporated in Mesostructured Silica Films.
P2860
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P2860
ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@en
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@nl
type
label
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@en
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@nl
prefLabel
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@en
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@nl
P2860
P356
P1476
ABCR, the ATP-binding cassette ...... lications for retinal disease.
@en
P2860
P304
11766-11774
P356
10.1074/JBC.M010152200
P407
P577
2001-01-23T00:00:00Z