Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
about
Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain.Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient miceDiscovery of molecular mechanisms of neuroprotection using cell-based bioassays and oligonucleotide arrays.Bioavailability of reduced nicotinamide-adenine-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy.Nicotinamide inhibits alkylating agent-induced apoptotic neurodegeneration in the developing rat brainThe biochemical pathways of central nervous system neural degeneration in niacin deficiency.Nicotinamide reduces hypoxic ischemic brain injury in the newborn ratIntracellular redox state revealed by in vivo (31) P MRS measurement of NAD(+) and NADH contents in brains.Targeting WNT, protein kinase B, and mitochondrial membrane integrity to foster cellular survival in the nervous system.NADH hyperoxidation correlates with enhanced susceptibility of aged rats to hypoxia.A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neuronsPostischemic oxidative stress promotes mitochondrial metabolic failure in neurons and astrocytes.Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection.Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury.Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and MitophagySynthesis of nicotinamide-based molecularly imprinted microspheres and in vitro controlled release studies.Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.Nicotinamide protects HCN2 cells from the free radical generating toxin, tertiary butylhydroperoxide (t-BuOOH).Differential lipid peroxidation, Mn superoxide, and bcl-2 expression contribute to the maturation-dependent vulnerability of oligodendrocytes to oxidative stress.Neuroprotective effects of nicotinamide after experimental spinal cord injury.Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons.Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin.Protective function of nicotinamide against ketamine-induced apoptotic neurodegeneration in the infant rat brain.Neuroprotection in Parkinson models varies with toxin administration protocol.Metallo-ROS in Alzheimer's disease: oxidation of neurotransmitters by CuII-beta-amyloid and neuropathology of the disease.
P2860
Q25255947-E00B9745-779B-4695-8D28-BF20599C211DQ28593143-245F0A1F-60FF-4284-B776-B897BADDD704Q30865041-DCD76166-C64C-4CFC-BFF5-50893C565326Q32138929-89F96954-20B4-4C37-8F1C-7CF88963E3E9Q34098881-C9EEC99E-7230-4E32-9A42-4295C043605AQ34443624-2C84F1CD-0ED1-4502-9D17-8C1605D403A8Q35135187-CE4EB714-AD9F-426C-910A-15EBA2B07BBCQ35262533-E79B59A6-33F0-4F22-AD41-CC34F091EC42Q35692773-EE0D6ABE-658F-4EFF-A5CC-8F543F9D4011Q35927086-DA277A3B-D6E9-4D07-875E-D73DC918B1C3Q36037588-9BD89EFB-C02C-4A58-8459-726C1BD83B64Q37348559-59818711-5A35-4A58-B1DD-DEDAF0A8D4E4Q37864604-2A39E1BB-B174-48B7-9E4D-35B5A895F94FQ38170006-15F5A93B-8D90-4B69-A144-744DCAEAC3EEQ39593372-39E595CA-1DD9-49BB-ADA6-E52323B10262Q41288627-2316A735-3AAB-487D-A3B5-646C17FCB32DQ43159248-670344CA-D891-441C-90AB-D7C2F7459F30Q43618382-66ACD07D-05F0-4C15-8896-7330F9EF6F98Q44046046-192A7D9B-1B7E-47CA-B9C9-B87ED37B20E7Q44412808-EC0B4001-3462-44D6-AE60-1D45D5190B09Q44455404-342825A3-1E70-47B3-8CD3-E0AE3B176004Q44753973-38282E8E-5B76-4A3F-8AE0-942A6F704662Q45973938-D3D6D008-2BB7-4DF3-8D27-1A496D9D5748Q46648285-546750A0-E430-411F-9C0D-9D5B180D4A23Q48204662-A3A5DCEC-9F21-4FA2-8BF8-0489A5CB8E97Q48343782-6E9E0C00-33C1-4F30-A373-D0265E29F656Q53285683-1E8C8F10-7079-47D9-A5F2-E4E82716A356
P2860
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@en
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@nl
type
label
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@en
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@nl
prefLabel
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@en
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@nl
P2093
P1476
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.
@en
P2093
L K Klaidman
S K Mukherjee
P304
P356
10.1016/S0304-4165(00)00181-1
P577
2001-02-01T00:00:00Z