The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates.
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The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosisMycobacterial phenolic glycolipid virulence factor biosynthesis: mechanism and small-molecule inhibition of polyketide chain initiationPCR screening reveals considerable unexploited biosynthetic potential of ansamycins and a mysterious family of AHBA-containing natural products in actinomycetes.Combinatorial biosynthesis--potential and problems.Anthranilate-activating modules from fungal nonribosomal peptide assembly linesBiosynthesis of 3,5-AHBA-derived natural products.The enzymology of combinatorial biosynthesis.Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli.Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekiiThe biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.Progress in Understanding the Genetic Information and Biosynthetic Pathways behind Amycolatopsis Antibiotics, with Implications for the Continued Discovery of Novel Drugs.Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699.Extraction, purification, and identification of yersiniabactin, the siderophore of Yersinia pestis.Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism.Modification of rifamycin polyketide backbone leads to improved drug activity against rifampicin-resistant Mycobacterium tuberculosis.Genetics and Genomics of the Genus Amycolatopsis.Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis.Reduction of carboxylic acids by Nocardia aldehyde oxidoreductase requires a phosphopantetheinylated enzyme.Two genes, rif15 and rif16, of the rifamycin biosynthetic gene cluster in Amycolatopsis mediterranei likely encode a transketolase and a P450 monooxygenase, respectively, both essential for the conversion of rifamycin SV into B.
P2860
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P2860
The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
The loading module of rifamyci ...... nce for substituted benzoates.
@en
The loading module of rifamyci ...... nce for substituted benzoates.
@nl
type
label
The loading module of rifamyci ...... nce for substituted benzoates.
@en
The loading module of rifamyci ...... nce for substituted benzoates.
@nl
prefLabel
The loading module of rifamyci ...... nce for substituted benzoates.
@en
The loading module of rifamyci ...... nce for substituted benzoates.
@nl
P2093
P356
P1433
P1476
The loading module of rifamyci ...... nce for substituted benzoates.
@en
P2093
P304
P356
10.1021/BI010080Z
P407
P577
2001-05-01T00:00:00Z