Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
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Regulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasivenessMystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growthINTS6/DICE1 inhibits growth of human androgen-independent prostate cancer cells by altering the cell cycle profile and Wnt signalingBikunin target genes in ovarian cancer cells identified by microarray analysisDevelopment of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics.The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.Mechanisms by which IGF-I may promote cancerSomething old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationProprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growthA twenty-first century cancer epidemic caused by obesity: the involvement of insulin, diabetes, and insulin-like growth factorsHereditary Influence in Thoracic Aortic Aneurysm and Dissection.The inhibitor of kappa B kinase-epsilon regulates MMP-3 expression levels and can promote lung metastasis.Increased insulin-like growth factor 1 receptor (IGF1R) expression in small cell lung cancer and the effect of inhibition of IGF1R expression by RNAi on growth of human small cell lung cancer NCI-H446 cell.Sustained production of a soluble IGF-I receptor by gutless adenovirus-transduced host cells protects from tumor growth in the liver.Suppression of type 1 Insulin-like growth factor receptor expression by small interfering RNA inhibits A549 human lung cancer cell invasion in vitro and metastasis in xenograft nude mice.Gene expression profiles in cells transformed by overexpression of the IGF-I receptor.The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251.The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells.IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin.Increased insulin-like growth factor-1 receptor mRNA expression predicts poor survival in immunophenotypes of early breast carcinoma.RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness.Matrix metalloproteinase-2 expression by vascular smooth muscle cells is mediated by both stimulatory and inhibitory signals in response to growth factors.Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency.
P2860
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P2860
Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Cooperative regulation of the ...... factor receptor beta subunit.
@en
Cooperative regulation of the ...... factor receptor beta subunit.
@nl
type
label
Cooperative regulation of the ...... factor receptor beta subunit.
@en
Cooperative regulation of the ...... factor receptor beta subunit.
@nl
prefLabel
Cooperative regulation of the ...... factor receptor beta subunit.
@en
Cooperative regulation of the ...... factor receptor beta subunit.
@nl
P2093
P2860
P356
P1476
Cooperative regulation of the ...... factor receptor beta subunit.
@en
P2093
P2860
P304
33608-33615
P356
10.1074/JBC.M102754200
P407
P577
2001-07-09T00:00:00Z