Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
about
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growthNovel therapeutic targets for pancreatic cancerARK5 is a tumor invasion-associated factor downstream of Akt signalingThe insulin-like growth factor system in cancerHepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosisPIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinasesThe IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.Evaluation of sphingolipid metabolism in renal cortex of rats with streptozotocin-induced diabetes and the effects of rapamycin.Microenvironmental regulation of chemokine (C-X-C-motif) receptor 4 in ovarian carcinomaOverexpression of muscarinic receptor 3 promotes metastasis and predicts poor prognosis in non-small-cell lung cancer.Mechanisms by which IGF-I may promote cancerMatriptase is involved in ErbB-2-induced prostate cancer cell invasionThe anti-angiogenic peptide, loop 6, binds insulin-like growth factor-1 receptor.RABEX-5 is upregulated and plays an oncogenic role in gastric cancer development by activating the VEGF signaling pathway.Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease.Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cellsHuman pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors.Mechanisms of action of rapamycin in gliomas.The effects and mechanisms of SLC34A2 in tumorigenesis and progression of human non-small cell lung cancer.The insulin and igf-I pathway in endocrine glands carcinogenesisExpression of phosphorylated mTOR and its regulatory protein is related to biological behaviors of ameloblastoma.Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer.AKT2 confers protection against aortic aneurysms and dissections.Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitionsThe insulin-like growth factor system as a potential therapeutic target in gastrointestinal stromal tumors.Estrogen receptor beta protects against in vivo injury in RPE cells.Lipid raft localization of epidermal growth factor receptor alters matrix metalloproteinase-1 expression in SiHa cells via the MAPK/ERK signaling pathway.Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype.Epithelial and mesenchymal phenotypic switchings modulate cell motility in metastasisHematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP.Beyond a tumor suppressor: Soluble E-cadherin promotes the progression of cancer.Increased insulin-like growth factor 1 receptor (IGF1R) expression in small cell lung cancer and the effect of inhibition of IGF1R expression by RNAi on growth of human small cell lung cancer NCI-H446 cell.Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies.Plasticity of tumor cell invasion: governance by growth factors and cytokines.Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor.Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion.PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome.Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMPDifferential localization of MT1-MMP in human prostate cancer tissue: role of IGF-1R in MT1-MMP expression.
P2860
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P2860
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@en
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@nl
type
label
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@en
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@nl
prefLabel
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@en
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@nl
P2860
P356
P1433
P1476
Type 1 insulin-like growth fac ...... via PI 3-kinase/Akt signaling.
@en
P2093
Donglei Zhang
Pnina Brodt
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206197
P407
P577
2003-02-01T00:00:00Z