Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model.
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Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin,Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dioneSurviving an Oxygen Atmosphere: DNA Damage and RepairBase-excision repair of oxidative DNA damageThermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin.Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping.Effects of atmospheric pressure plasmas on isolated and cellular DNA-a reviewCharacterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contextsChemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite.No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient miceMutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts.Mechanistic aspects of the formation of guanidinohydantoin from spiroiminodihydantoin under acidic conditions.Mechanisms of free radical-induced damage to DNA.8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stressNei deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin.Recent advances in the structural mechanisms of DNA glycosylasesComparison of Transition Metal-Mediated Oxidation Reactions of Guanine in Nucleoside and Single-Stranded Oligodeoxynucleotide Contexts.Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylases.Spirodi(iminohydantoin) products from oxidation of 2'-deoxyguanosine in the presence of NH4Cl in nucleoside and oligodeoxynucleotide contexts.Chemistry meets biology in colitis-associated carcinogenesisQuantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-beta-D-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MSThe NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structuresSynthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates.5-Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8-oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X-ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA ContextsBase and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA.Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer.pH-Dependent Equilibrium between 5-Guanidinohydantoin and Iminoallantoin Affects Nucleotide Insertion Opposite the DNA Lesion.Guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin induces mutations when bypassed by DNA polymerases and is a substrate for base excision repair.In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase.Unusual structural features of hydantoin lesions translate into efficient recognition by Escherichia coli FpgChemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosineKlenow Fragment Discriminates against the Incorporation of the Hyperoxidized dGTP Lesion Spiroiminodihydantoin into DNA.Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurementsInvestigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions.Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair.
P2860
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P2860
Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Characterization of hydantoin ...... anosine in a nucleoside model.
@en
Characterization of hydantoin ...... anosine in a nucleoside model.
@nl
type
label
Characterization of hydantoin ...... anosine in a nucleoside model.
@en
Characterization of hydantoin ...... anosine in a nucleoside model.
@nl
prefLabel
Characterization of hydantoin ...... anosine in a nucleoside model.
@en
Characterization of hydantoin ...... anosine in a nucleoside model.
@nl
P2093
P356
P1476
Characterization of hydantoin ...... anosine in a nucleoside model.
@en
P2093
P304
P356
10.1021/TX010072J
P577
2001-07-01T00:00:00Z