Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase.
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Pivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved IssuesScreening approaches to generating STAT inhibitors: Allowing the hits to identify the targetsCytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3STAT3 deletion sensitizes cells to oxidative stressSignals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytesAuto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survivalSequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hypoxia in lung microvascular endothelial cellsEnhancing or eliminating signals for cell survival to treat disease.Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro.The stem cell adjuvant with Exendin-4 repairs the heart after myocardial infarction via STAT3 activation.P53 inhibition exacerbates late-stage anthracycline cardiotoxicity.Peripartum cardiomyopathy: Euro Observational Research ProgramThe adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons.Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair.Calreticulin-STAT3 signaling pathway modulates mitochondrial function in a rat model of furazolidone-induced dilated cardiomyopathyPeripartum cardiomyopathy and dilated cardiomyopathy: different at heart.Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironmentMnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis.Network analysis of inflammatory genes and their transcriptional regulators in coronary artery disease.Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen speciesSDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury.Manganese superoxide dismutase: guardian of the powerhouse.Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules.Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms.Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cellsSignal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion.Cellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice.Interleukin 6-preconditioned neural stem cells reduce ischaemic injury in stroke mice.Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspectsInflammation and ischemia: macrophages activated by fibronectin fragments enhance the survival of injured cardiac myocytesBerberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenationChronic treatment of mice with leukemia inhibitory factor does not cause adverse cardiac remodeling but improves heart function.Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age.A microRNA links prolactin to peripartum cardiomyopathy.Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress.Role of STAT3 in angiotensin II-induced hypertension and cardiac remodeling revealed by mice lacking STAT3 serine 727 phosphorylation.
P2860
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P2860
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Activation of signal transduce ...... anganese superoxide dismutase.
@en
Activation of signal transduce ...... anganese superoxide dismutase.
@nl
type
label
Activation of signal transduce ...... anganese superoxide dismutase.
@en
Activation of signal transduce ...... anganese superoxide dismutase.
@nl
prefLabel
Activation of signal transduce ...... anganese superoxide dismutase.
@en
Activation of signal transduce ...... anganese superoxide dismutase.
@nl
P2093
P356
P1433
P1476
Activation of signal transduce ...... anganese superoxide dismutase.
@en
P2093
Darville MI
Eizirik DL
Funamoto M
Kishimoto T
Kunisada K
P304
P356
10.1161/HC3401.095947
P407
P577
2001-08-01T00:00:00Z