Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
about
In vitro and in vivo modifications of recombinant and human IgG antibodiesLC-MS/MS peptide mapping with automated data processing for routine profiling of N-glycans in immunoglobulins.Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylationEndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selectivity and can be used for rapid quantification of high-mannose glycansUltrafast and high-throughput N-glycan analysis for monoclonal antibodies.High-resolution MS for structural characterization of protein therapeutics: advances and future directions.Recent advances in the understanding of biological implications and modulation methodologies of monoclonal antibody N-linked high mannose glycans.Tailoring recombinant protein quality by rational media design.Galactose supplementation enhance sialylation of recombinant Fc-fusion protein in CHO cell: an insight into the role of galactosylation in sialylation.Impact of cell culture on recombinant monoclonal antibody product heterogeneity.Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation.Glycoengineering of CHO Cells to Improve Product Quality.Effects of cell culture conditions on antibody N-linked glycosylation--what affects high mannose 5 glycoform.Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactose.Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab.Mannose metabolism in recombinant CHO cells and its effect on IgG glycosylation.Impact of host cell line choice on glycan profile.Advanced model-based control strategies for the intensification of upstream and downstream processing in mAb production.Animal Cell Expression Systems.Cell culture media supplementation of infrequently used sugars for the targeted shifting of protein glycosylation profiles.Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.Combining metabolic and process engineering strategies to improve recombinant glycoprotein production and quality.Glycoprofiling effects of media additives on IgG produced by CHO cells in fed-batch bioreactors.
P2860
Q26859713-ABFB1D51-6D0D-4D50-80AD-F4F407BFCF94Q30784999-52FAF35F-BDA7-4595-9E98-34DAA7477ABBQ35123102-DDE195F5-E910-4EEA-A414-D10B2A82B6DDQ35686671-7B0E8BCE-DBE5-4FBA-971E-EE33C3FB7C52Q35990992-AF88BD4F-F101-4314-8590-0AFE7E0F8202Q38110611-2119A955-6D57-4CF7-A3B3-5EEDF0D0CFF2Q38224264-A1F8EAC0-F82E-45C9-9E05-0CE510877BA4Q38416739-93BA4808-2C45-4DF4-B3F5-09B9E81AA5D8Q38880290-77AA17FF-98C2-4A02-BDD9-D8CE764AFDD3Q38907094-D0D36D4E-BAC4-4ACC-8F91-036F854F9344Q38956580-88DB7F1F-DFDB-4AC0-9159-B689171D08C1Q39143876-DA374DF5-FDDF-4AD3-B475-85D6B37A891CQ39298073-A53910F4-9E55-430C-A30E-74B999AA7E50Q39545373-C048AA92-408C-476A-B0C5-8BA30055A189Q39590627-F982DC39-633E-4B74-994A-239C4BC2B5BCQ43278365-0926E172-DBD5-4765-AAC2-DBDBB9FFFD51Q46021617-24AC925B-8C8D-450B-88FF-8BC5553E675DQ47269842-3136D92F-445D-4000-9153-1CA6FAC481F8Q47396419-1D97B74F-F63C-44A2-A376-F4B3059ADDEEQ47406183-AA4947E4-B24B-443F-B806-115320C55629Q47598608-8B355FF1-93CE-4892-908F-33BAB20CECBFQ47656437-5256E743-BB54-4256-BB67-08CF814373F6Q47660951-8E6B23AA-9C4D-4C9A-8E45-B98BF0963CD4Q51741789-24BA64F5-B9F9-4572-B2AC-D8CBAAC93409
P2860
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@en
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@nl
type
label
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@en
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@nl
prefLabel
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@en
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@nl
P2093
P2860
P356
P1476
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
@en
P2093
P2860
P304
P356
10.1002/BIT.10022
P577
2001-10-01T00:00:00Z