Population pharmacokinetic/pharmacodynamic modeling of drug-induced adverse effects of a novel homocamptothecin analog, elomotecan (BN80927), in a Phase I dose finding study in patients with advanced solid tumors.
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Pharmacodynamic modeling of adverse effects of anti-cancer drug treatmentRelation between acute and long-term cognitive decline after surgery: Influence of metabolic syndrome.Bringing Model-Based Prediction to Oncology Clinical Practice: A Review of Pharmacometrics Principles and Applications.A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment.Discovery of 7-Methyl-10-Hydroxyhomocamptothecins with 1,2,3-Triazole Moiety as Potent Topoisomerase I Inhibitors.Topoisomerases: Resistance versus Sensitivity, How Far We Can Go?Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive AgentsCamptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?
P2860
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P2860
Population pharmacokinetic/pharmacodynamic modeling of drug-induced adverse effects of a novel homocamptothecin analog, elomotecan (BN80927), in a Phase I dose finding study in patients with advanced solid tumors.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@en
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@nl
type
label
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@en
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@nl
prefLabel
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@en
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@nl
P2093
P2860
P1476
Population pharmacokinetic/pha ...... ts with advanced solid tumors.
@en
P2093
Ana Perez-Mayoral
Concepción Peraire
Elena Soto
Frédérique Cvitkovic
Joan Pruñonosa
Josep-María Cendrós
Paola Principe
Patrick Delavault
Rosendo Obach
Thierry Lesimple
P2860
P2888
P304
P356
10.1007/S00280-012-1906-Y
P577
2012-06-15T00:00:00Z
P6179
1050604093