Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
about
Refined structure of dimeric diphtheria toxin at 2.0 A resolutionIcmQ in the Type 4b Secretion System Contains an NAD+ Binding DomainCrystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylationDPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.Purification and cloning of pierisin-2, an apoptosis-inducing protein from the cabbage butterfly, Pieris brassicae.The family of bacterial ADP-ribosylating exotoxinsRole of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen.Male seminal fluid proteins are essential for sperm storage in Drosophila melanogaster.Molecular cloning of an apoptosis-inducing protein, pierisin, from cabbage butterfly: possible involvement of ADP-ribosylation in its activityIdentification of a single amino acid substitution in the diphtheria toxin A chain of CRM 228 responsible for the loss of enzymatic activity.Molecular and biological characterization of Streptococcal SpyA-mediated ADP-ribosylation of intermediate filament protein vimentin.A d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway.Probing the function of Drosophila melanogaster accessory glands by directed cell ablation.Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin.Novel bacterial ADP-ribosylating toxins: structure and function.Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins.Active site mutations of Pseudomonas aeruginosa exotoxin A. Analysis of the His440 residue.Probing the structure-activity relationship of Escherichia coli LT-A by site-directed mutagenesis.Membrane translocation of diphtheria toxin carrying passenger protein domains.Construction and expression of plasmids containing mutated diphtheria toxin A-chain-coding sequences.Importance of ADP-ribosylation in the morphological changes of PC12 cells induced by cholera toxin.Association between diphtheria toxin A- and B-fragment and their fusion proteinsTransition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin.Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin.A re-evaluation of the role of histidine-426 within Pseudomonas aeruginosa exotoxin A.Unusual conformation of nicotinamide adenine dinucleotide (NAD) bound to diphtheria toxin: a comparison with NAD bound to the oxidoreductase enzymes.Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway.Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.Cytotoxic activity of a recombinant chimaeric protein between Pseudomonas aeruginosa exotoxin A and Corynebacterium diphtheriae diphtheria toxin.Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding.Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.Site-directed mutagenic alteration of potential active-site residues of the A subunit of Escherichia coli heat-labile enterotoxin. Evidence for a catalytic role for glutamic acid 112.
P2860
Q24675451-41CB356F-B473-4F12-A9F7-50D323970D0AQ27679067-216ACA02-BFA5-436F-A32C-040E9DECB8A8Q27733160-38FD31BD-4E08-4207-B6D6-8024F617F1FEQ27932660-149F364B-6C2E-4A2E-B3AD-4C341D277A74Q33916416-EAE73388-9B64-4A4D-AF93-5BFA5ACE7E90Q34058617-57C680E8-6269-4EA6-8D8D-6B55C27A8B40Q34544082-A13DEBED-0724-4A96-B671-AB98AD63F395Q34607980-E6C4B8BD-F578-40EA-A2C9-25AC39DAA6EFQ35626584-4DB97EAE-59F6-4EC1-9822-130FF75DDE84Q35967713-8A1D3E59-8374-4255-BB47-6FF556D90362Q36033302-7424D95B-E38D-46DC-BD77-A3B50B2CB6B6Q36458568-536E54F9-DBDE-4739-A61C-2B2EA24FF840Q36509632-AE3C7080-B5B0-4270-AADE-216E20855C8CQ36972449-ED3349E5-CD02-419C-815F-87FCC5069428Q38229329-0BE45761-94A7-4762-AFF8-6AB670580E2FQ38298647-3020F31E-C7D0-4760-A75D-2E6E099E5D50Q38299813-5DB22567-041F-438E-AC90-A68FF111F322Q38303976-BD3AECA9-45A6-4A1B-97A8-75DFBC48D713Q40147594-239433B9-AC93-45C5-AA6D-5E48FE3C5607Q40155563-83989EE3-AD96-456B-B0DB-4674D2C1C280Q40375503-11C6DC2D-C1C3-450B-B2B4-44E0CF2BFE34Q41825211-6E1FDE26-5949-4EC0-B119-25DACD87B86FQ42016501-169F1242-ECBA-4E74-A796-EE3066CCB8BFQ42060384-1B4257DA-351F-44EB-A818-949DEB91D119Q42139924-233981FB-8431-434C-A649-01240BD058A8Q42167298-EEF57D47-86C7-4B81-AC2E-13445ECBCFFFQ42637135-A6BE99FD-6EC6-4367-B15E-1F34DD1815F0Q42801758-603BBB62-84F7-434A-8FAE-6E5DDC3F1DEAQ42819588-C2EB5474-8380-401A-94EE-91903656554EQ44635768-1E54AFA2-1B16-4428-85E2-297B1E676641Q52540113-904D6252-D684-410A-8B2F-236EE1445401Q54598155-D46DB222-559A-4FAF-ADD9-ABCD20541724
P2860
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@en
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@nl
type
label
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@en
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@nl
prefLabel
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@en
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@nl
P2093
P356
P1433
P1476
Active-site mutations of dipht ...... ic acid, glutamine, or serine.
@en
P2093
P304
P356
10.1021/BI00489A021
P407
P577
1990-09-01T00:00:00Z