Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility.
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Oxidative stress, mitochondrial dysfunction, and agingIs the oxidative stress theory of aging dead?Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive systemOxidative stress and adult neurogenesis--effects of radiation and superoxide dismutase deficiencyParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsMitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function.Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease.Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?When a theory of aging ages badly.Overexpression of antioxidant enzymes in diaphragm muscle does not alter contraction-induced fatigue or recovery.Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes.Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin.Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.Targeting the oncogene B lymphoma deregulator IgH 3' regulatory region does not impede the in vivo inflammatory response in mice.Redox reactions in mammalian spermatogenesis and the potential targets of reactive oxygen species under oxidative stressIsocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutaseTransgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex.Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.Mitochondrial antioxidative capacity regulates muscle glucose uptake in the conscious mouse: effect of exercise and diet.Controlled and localized genetic manipulation in the brain.Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.The overexpression of major antioxidant enzymes does not extend the lifespan of mice.Modulation of MnSOD in Cancer:Epidemiological and Experimental Evidence.MnSODtg mice control myocardial inflammatory and oxidative stress and remodeling responses elicited in chronic Chagas disease.NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.Overexpression of Mn superoxide dismutase does not increase life span in mice.Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodentRedox balance- and radiation-mediated alteration in hippocampal neurogenesis.Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease.The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity.Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development.Is human aging still mysterious enough to be left only to scientists?
P2860
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P2860
Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Strain-dependent high-level ex ...... ation and decreased fertility.
@en
Strain-dependent high-level ex ...... ation and decreased fertility.
@nl
type
label
Strain-dependent high-level ex ...... ation and decreased fertility.
@en
Strain-dependent high-level ex ...... ation and decreased fertility.
@nl
prefLabel
Strain-dependent high-level ex ...... ation and decreased fertility.
@en
Strain-dependent high-level ex ...... ation and decreased fertility.
@nl
P2093
P1476
Strain-dependent high-level ex ...... ation and decreased fertility.
@en
P2093
Carlson EJ
Epstein CJ
Oberley TD
P304
P356
10.1016/S0891-5849(01)00686-4
P577
2001-10-01T00:00:00Z